J
John A. Kairalla
Researcher at University of Florida
Publications - 66
Citations - 1197
John A. Kairalla is an academic researcher from University of Florida. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 14, co-authored 50 publications receiving 847 citations. Previous affiliations of John A. Kairalla include East Tennessee State University.
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Adaptive trial designs: a review of barriers and opportunities
TL;DR: This work focuses on the design principles and research issues that lead to particular designs being appealing or unappealing in particular applications, and describes a number of current barriers and suggestions for overcoming them in order to promote wider use of appropriate adaptive designs.
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Dasatinib plus intensive chemotherapy in children, adolescents, and young adults with philadelphia chromosome–positive acute lymphoblastic leukemia: Results of children’s oncology group trial AALL0622
William B. Slayton,Kirk R. Schultz,John A. Kairalla,Meenakshi Devidas,Xinlei Mi,Michael A. Pulsipher,Bill H. Chang,Charles G. Mullighan,Ilaria Iacobucci,Lewis B. Silverman,Michael J. Borowitz,Andrew J. Carroll,Nyla A. Heerema,Julie M. Gastier-Foster,Brent L. Wood,Sherri L. Mizrahy,Thomas E. Merchant,Valerie I. Brown,Lance Sieger,Marilyn J. Siegel,Elizabeth A. Raetz,Naomi J. Winick,Mignon L. Loh,William L. Carroll,Stephen P. Hunger +24 more
TL;DR: Dasatinib was well tolerated with chemotherapy and provided outcomes similar to those with imatinib in COG AALL0031, where all patients received cranial irradiation.
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Adaptive clinical trials: progress and challenges.
TL;DR: This review examines the different types of adaptive designs for sample size re-estimation in order to clarify the controversy surrounding the use of these methods and summarizes the existing methods and current controversies with the intent of providing a clarification.
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Effects of a Father-Based In-Home Intervention on Perceived Stress and Family Dynamics in Parents of Children With Autism
Roxanna M. Bendixen,Jennifer H. Elder,Susan Donaldson,John A. Kairalla,Greg Valcante,Richard E. Ferdig +5 more
TL;DR: Parents of children with autism report high rates of stress; fathers were taught an intervention designed to improve their child's social reciprocity and communication; they then trained mothers, and parenting styles were significantly different before and after intervention.
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GLUMIP 2.0: SAS/IML Software for Planning Internal Pilots
TL;DR: The latest version of the free SAS/IML software makes it easy to perform exact power analysis for internal pilots under the GLUM framework with independent Gaussian errors and fixed predictors.