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John D. Estes

Researcher at National Institutes of Health

Publications -  25
Citations -  1043

John D. Estes is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Virus & Murine leukemia virus. The author has an hindex of 16, co-authored 25 publications receiving 1040 citations.

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A Spontaneous Lower Motor Neuron Disease Apparently Caused by Indigenous Type-C RNA Virus in Wild Mice

TL;DR: Experimental transmission evidence indicated that both the neurologic and lymphomatous disorders almost certainly were caused by the indigenous type-C virus.
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Experimental Transmission of Feline Fibrosarcoma to Cats and Dogs

TL;DR: Prenatal inoculation of cat and dog foetuses is particularly effective in tumour transmission and postnatal dogs bearing FSV induced fibrosarcomas provide antisera suitable for detecting the feline C-type RNA tumour virus antigens in the complement fixation test.
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Studies of mouse polyoma virus infection : i. procedures for quantitation and detection of virus

TL;DR: Three procedures have been compared for usefulness in titration and detection of polyoma virus: production of cytopathic effect in mouse embryo tissue culture, production of HI antibody after inoculation into weanling mice (MAP test), and production of tumors in suckling hamsters during a 3 to 5 week observation period.
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Isolation of a Neurotropic Type C Virus

TL;DR: A neurogenic paralysis of the lower limb can be induced and serially transmitted in mice by a nontransforming type C virus strain that originated in an embryo of a wild mouse and exerted a neurotropic effect on the anterior horn neurons.
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Dietary fat affects immune response, production of antiviral factors, and immune complex disease in nzb/nzw mice.

TL;DR: The results suggest that the type of fat in the diet could affect the serum level of different immunoglobulin classes, and the amount of dietary lipids alone can influence cellular and humoral immune responses and the spontaneous development of immune complex disease.