J
John H. Eckfeldt
Researcher at University of Minnesota
Publications - 245
Citations - 23329
John H. Eckfeldt is an academic researcher from University of Minnesota. The author has contributed to research in topics: Population & Renal function. The author has an hindex of 58, co-authored 244 publications receiving 21496 citations. Previous affiliations of John H. Eckfeldt include Research Triangle Park & College of American Pathologists.
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Journal ArticleDOI
The 25-hydroxyvitamin D3 C-3 epimer: Distribution, correlates, and reclassification of 25-hydroxyvitamin D status in the population-based Atherosclerosis Risk in Communities Study (ARIC)
Pamela L. Lutsey,John H. Eckfeldt,Ejovwoke R. Ogagarue,Aaron R. Folsom,Erin D. Michos,Myron D. Gross +5 more
TL;DR: Characteristics of the D3 epimer within the community-based ARIC cohort are described and epimer levels were associated with participant characteristics in a manner similar to that typically observed for 25(OH)D3.
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Plasma homocysteine and its association with carotid intimal-medial wall thickness and prevalent coronary heart disease: NHLBI Family Heart Study.
TL;DR: The present finding of a positive association between tHcy and intimal-medial wall thickness strengthens the in vitro finding of the stimulating effect of homocysteine on vascular smooth muscle cell growth, which may be an important mechanism through which mildly elevated plasma tHCy promotes atherosclerosis.
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Novel association between plasma matrix metalloproteinase-9 and risk of incident atrial fibrillation in a case-cohort study: the Atherosclerosis Risk in Communities Study
Rachel R. Huxley,Faye L. Lopez,Richard F. MacLehose,John H. Eckfeldt,David Couper,Catherine Leiendecker-Foster,Ron C. Hoogeveen,Lin Y. Chen,Elsayed Z. Soliman,Sunil K. Agarwal,Alvaro Alonso +10 more
TL;DR: The findings suggest that elevated levels of MMP-9 are independently associated with increased risk of AF, however, it remains to be determined whether the observed relationship reflects the impact of atrial fibrosis or more generalized fibrosis on risk of incident AF.
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Antihypertensive therapy, the α-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study
Barry R. Davis,Donna K. Arnett,Eric Boerwinkle,Charles E. Ford,C. Leiendecker-Foster,Michael B. Miller,Henry R. Black,John H. Eckfeldt +7 more
TL;DR: The α-adducin gene is not an important modifier of antihypertensive treatment on cardiovascular risk, but women Trp allele carriers may have increased CHD risk if treated with C versus A or L.
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A sensitive assay of transthyretin (prealbumin) in human cerebrospinal fluid in nanogram amounts by ELISA.
G. T. Vatassery,G. T. Vatassery,Hung T. Quach,Hung T. Quach,W. E. Smith,W. E. Smith,B. A. Benson,B. A. Benson,John H. Eckfeldt,John H. Eckfeldt +9 more
TL;DR: The transthyretin concentrations in CSF did not correlate with total CSF protein concentration or age of the subject, which suggests that synthesis of tranSthy retin in the brain and peripheral tissues is under similar biological control in normal subjects.