J
John I. Risinger
Researcher at Michigan State University
Publications - 96
Citations - 7529
John I. Risinger is an academic researcher from Michigan State University. The author has contributed to research in topics: Endometrial cancer & Cancer. The author has an hindex of 44, co-authored 93 publications receiving 7166 citations. Previous affiliations of John I. Risinger include University of North Carolina at Chapel Hill & National Institutes of Health.
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Proceedings ArticleDOI
Abstract 3375: Normal viability of Kai1/CD82 deficient mice
John I. Risinger,Mary C. Custer,Lionel Feigenbaum,R. Mark Simpson,Shelley B. Hoover,Josh Webster,Gadisetti V.R. Chandramouli,Lino Tessarollo,J. Carl Barrett +8 more
TL;DR: Interestingly mice deficient in KAI1/CD82 showed no obvious genotypes associated defects in any of these processes as compared to their wild-type littermates and displayed no genotype associated abnormalities after 12 or 18 months of life.
Journal ArticleDOI
Improving Risk Assessment for Metastatic Disease in Endometrioid Endometrial Cancer Patients Using Molecular and Clinical Features: An NRG Oncology/Gynecologic Oncology Group Study
Yovanni Casablanca,Guisong Wang,Heather A. Lankes,Chunqiao Tian,D. Nicholas Bateman,Caela R. Miller,Nicole P. Chappell,Laura J. Havrilesky,A. Wallace,Nilsa C. Ramirez,David Miller,Julie Oliver,Dave Mitchell,Tracy Litzi,Brian Blanton,William J. Lowery,John I. Risinger,Chad A. Hamilton,Neil T. Phippen,Thomas P. Conrads,David G. Mutch,Katherine M. Moxley,Roger B. Lee,Floor J. Backes,Michael J. Birrer,Kathleen M. Darcy,G. Larry Maxwell +26 more
TL;DR: The molecular score, referred to as MS7, was more accurate at judging the chance of nodal and distant metastasis than clinical factors like grade 3 disease and myometrial invasion and was associated with lower progression-free and overall survival.
Proceedings ArticleDOI
Abstract LB-042: Successful tumor formation following xenotransplantation of primary human ovarian cancer cells into severe combined immunodeficient (SCID) pigs
Adeline N. Boettcher,Matti Kiupel,Malavika K. Adur,Emiliano Cocco,Alessandro D. Santin,Sara E. Charley,John I. Risinger,Christopher K. Tuggle,Erik M. Shapiro +8 more
TL;DR: Confirmation that OSPC-ARK1 cells can form tumors in SCID pigs substantiates further development of orthotopic models of OvCa in pigs for researching improved OvCa therapeutic and diagnostic methods.
Journal ArticleDOI
MIG-6 Is Critical for Progesterone Responsiveness in Human Complex Atypical Hyperplasia and Early-Stage Endometrial Cancer
TL;DR: In this article , the authors showed that loss of MIG-6 and PGR and activation of pAKT lead to P4 resistance in CAH and EEC patients, and showed that stromal PGR levels are significantly higher in P4-responsive women compared to p4-resistant women, whereas epithelial PGR expression was not different.