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John M. Close

Researcher at University of Pittsburgh

Publications -  55
Citations -  3880

John M. Close is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Lung cancer & Masseter muscle. The author has an hindex of 29, co-authored 55 publications receiving 3635 citations.

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Minimally Invasive Esophagectomy: Outcomes in 222 Patients

TL;DR: In this single institution experience, MIE offers results as good as or better than open operation in the authors' center with extensive minimally invasive and open experience, with a lower mortality rate (1.4%) and shorter hospital stay (7 days) than most open series.
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Obliterative bronchiolitis after lung and heart-lung transplantation: An analysis of risk factors and management

TL;DR: Recipients with obliterative bronchiolitis detected in the preclinical stage were significantly more likely to be in remission than recipients who had clinical disease at the time of diagnosis and results indicate that acute rejection is the most significant risk factor for development of obliteration and that obliteration responds to treatment with augmented immunosuppression when it is detected early by surveillance transbronchial biopsy.
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Anatomic Segmentectomy in the Treatment of Stage I Non-Small Cell Lung Cancer

TL;DR: Anatomic segmentectomy outcomes compare favorably with standard lobectomy for stage I NSCLC and Margin/tumor ratios exceeding 1 were associated with a significant reduction in recurrence rates compared with ratios of less than 1, which should be considered as primary therapy when such margins are not obtainable with segmentectomy in the good-risk patient.
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Nanostructured calcium phosphates (NanoCaPs) for non-viral gene delivery: influence of the synthesis parameters on transfection efficiency.

TL;DR: A novel method to consistently synthesize efficient, nano-sized, mono-dispersed CaP-pDNA particles by optimizing both the stoichiometry (Ca/P ratio) of the CaP particles as well as the mode in which the calcium and phosphate precursor solutions are mixed.
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Margin and local recurrence after sublobar resection of non-small cell lung cancer.

TL;DR: Margin is an important consideration after sublobar resection of stage I NSCLC and segmentectomy appears to be a better choice of SR when this is chosen as therapy.