J
John M. Grange
Researcher at University College London
Publications - 51
Citations - 1652
John M. Grange is an academic researcher from University College London. The author has contributed to research in topics: Tuberculosis & Mycobacterium vaccae. The author has an hindex of 25, co-authored 51 publications receiving 1579 citations.
Papers
More filters
Journal Article
A study of maternal mortality at the University Teaching Hospital, Lusaka, Zambia: the emergence of tuberculosis as a major non-obstetric cause of maternal death.
TL;DR: Despite improved obstetric services, the maternal mortality ratios at UTH, Lusaka, Zambia have increased eight-fold over the past two decades, mainly due to non-obstetric causes of death.
Journal ArticleDOI
Protection against melanoma by vaccination with Bacille Calmette-Guerin (BCG) and/or vaccinia: an epidemiology-based hypothesis on the nature of a melanoma risk factor and its immunological control.
TL;DR: The present hypothesis is in accordance with the concept that immune dysregulation due to adverse environmental impacts is a risk factor not only for some autoimmune disorders, as previously described, but also for certain malignancies such as melanoma.
Journal ArticleDOI
Treatment of tuberculosis: present status and future prospects
Philip Onyebujoh,Alimuddin Zumla,Isabella Ribeiro,Roxana Rustomjee,Peter Mwaba,Melba Gomes,John M. Grange +6 more
TL;DR: The current status of TB management is summarized and recent thinking and strategy adjustments required for the control of TB in settings of high HIV prevalence are described.
Journal Article
Immunotherapy with Mycobacterium vaccae in patients with newly diagnosed pulmonary tuberculosis: a randomised controlled trial
Philip Onyebujoh,JB Levin,FB Fourie,Garhiram,LC Tembe,NP Phili,Tcp Mthiyane,T Moniwa,G Bayer,IM Ramajoe,Tab Mncwabe,Lgm Mallisar,Tnm Saul,Thfg Jackson,S Suparsad,P. E. M. Fine,Djs Pendlebury,E Fine,I Houghton,J Clyde,HP Vos,N Padayatchi,A Pala,A Ramjee,M Ramjee,J Ramdeen,IH Masters,G Osbourne,K Naidu,S Bamba,B Mazur,R Czarnocki,K Landers,G Ndlovu,N Maphumulo,AW Sturm,J Moodley,C Pillay,L Roux,R Moodley,A Sarawan,T Jali,F Manickam,A Smith,Gopaul,T Durosanmi,R Moonsammy,P Wyld,J McCallum,C Fulton,K Bisset,S Henderson,D Stewart,O Nticinka,D Watson,N Tuckwell,D Kennard,Jl Stanford,Graham A. W. Rook,John M. Grange,AA Zumla,E Bateman,P Hopwell,J Darbyshire,L Geiter,A Nunn,K Weyer,Durban Immunotherapy Trial Grp +67 more
TL;DR: M. vaccae immunotherapy has no benefit when added to standard antituberculosis chemotherapy, and the time to a negative sputum culture in the first 8 weeks was the primary outcome.
Journal ArticleDOI
Inverse association between melanoma and previous vaccinations against tuberculosis and smallpox: results of the FEBIM study.
Anisette Pfahlberg,K. F. Kölmel,John M. Grange,Giuseppe Mastrangelo,Bernd Krone,I.N. Botev,Marianne Niin,Claus Seebacher,Daniel Lambert,Raphael Shafir,Daniela Schneider,E. M. Kokoschka,Ulrich R. Kleeberg,Wolfgang Uter,Olaf Gefeller +14 more
TL;DR: It is concluded that bacille Calmette-Guérin vaccination and vaccinia vaccination may lower melanoma risk and current immunologic theory of melanoma development provides a sound basis for understanding the biologic plausibility of the findings.