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Modern Applied Statistics With S

25. Multiple Imputation for Nonresponse in Surveys. By D. B. Rubin. ISBN 0 471 08705 X. Wiley, Chichester, 1987. 258 pp. £30.25.

Multiple Imputation for Nonresponse in Surveys

Although there has been considerable progress in reducing cancer incidence in the United States, the number of cancer survivors continues to increase due to the aging and growth of the population and improvements in survival rates. As a result, it is increasingly important to understand the unique medical and psychosocial needs of survivors and be aware of resources that can assist patients, caregivers, and health care providers in navigating the various phases of cancer survivorship. To highlight the challenges and opportunities to serve these survivors, the American Cancer Society and the National Cancer Institute estimated the prevalence of cancer survivors on January 1, 2012 and January 1, 2022, by cancer site. Data from Surveillance, Epidemiology, and End Results (SEER) registries were used to describe median age and stage at diagnosis and survival; data from the National Cancer Data Base and the SEER-Medicare Database were used to describe patterns of cancer treatment. An estimated 13.7 million Americans with a history of cancer were alive on January 1, 2012, and by January 1, 2022, that number will increase to nearly 18 million. The 3 most prevalent cancers among males are prostate (43%), colorectal (9%), and melanoma of the skin (7%), and those among females are breast (41%), uterine corpus (8%), and colorectal (8%). This article summarizes common cancer treatments, survival rates, and posttreatment concerns and introduces the new National Cancer Survivorship Resource Center, which has engaged more than 100 volunteer survivorship experts nationwide to develop tools for cancer survivors, caregivers, health care professionals, advocates, and policy makers.

https://onlinelibrary.wiley.com/doi/pdf/10.3322/caac.21149

Cancer treatment and survivorship statistics, 2012

The central dogma of gene expression is that DNA is transcribed into messenger RNAs, which in turn serve as the template for protein synthesis. The discovery of extensive transcription of large RNA transcripts that do not code for proteins, termed long noncoding RNAs (lncRNAs), provides an important new perspective on the centrality of RNA in gene regulation. Here, we discuss genome-scale strategies to discover and characterize lncRNAs. An emerging theme from multiple model systems is that lncRNAs form extensive networks of ribonucleoprotein (RNP) complexes with numerous chromatin regulators and then target these enzymatic activities to appropriate locations in the genome. Consistent with this notion, lncRNAs can function as modular scaffolds to specify higher-order organization in RNP complexes and in chromatin states. The importance of these modes of regulation is underscored by the newly recognized roles of long RNAs for proper gene control across all kingdoms of life.

/pdf/genome-regulation-by-long-noncoding-rnas-3sihgaljj1.pdf

Genome Regulation by Long Noncoding RNAs

EAU–ESTRO–SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent

2: Contemporary Practice Patterns in Management of Bladder Exstrophy in Newborns

Mp40-13 optimized clinical algorithm to combine testing of serum phi and urinary pca3 to improve prostate cancer detection by reducing unnecesary biopsy

Re: The increasing incidence of newborn circumcision: Data from the nationwide inpatient sample [6] (multiple letters)

Genome-Wide Analysis Identifies Rare Copy Number Variations Associated with Inflammatory Bowel Disease

Mp26-07 in-office freehand transperineal template mapping biopsy performed under local anesthesia using a novel needle guide: feasible, safe, and effective for cancer detection

John T. Wei

Papers

2: Contemporary Practice Patterns in Management of Bladder Exstrophy in Newborns

Mp40-13 optimized clinical algorithm to combine testing of serum phi and urinary pca3 to improve prostate cancer detection by reducing unnecesary biopsy

Re: The increasing incidence of newborn circumcision: Data from the nationwide inpatient sample [6] (multiple letters)

Genome-Wide Analysis Identifies Rare Copy Number Variations Associated with Inflammatory Bowel Disease

Mp26-07 in-office freehand transperineal template mapping biopsy performed under local anesthesia using a novel needle guide: feasible, safe, and effective for cancer detection