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Showing papers in "The Journal of Urology in 2006"


Journal ArticleDOI
TL;DR: Cell line experiments suggest that the androgen-responsive promoter elements of TMPRSS2 mediate the overexpression of ETS family members in prostate cancer.

2,228 citations


Journal ArticleDOI
TL;DR: In this article, the PSA doubling time (PSADT) data of men undergoing radical prostatectomy and subsequent biochemical re-currence was used to diagnose distant metastasis.

803 citations



Journal ArticleDOI
TL;DR: Long-term overall and progression-free survival after treatment with GC or MVAC are similar, and the role of GC as a standard of care in patients with locally advanced or metastatic TCC is strengthened.

677 citations


Journal ArticleDOI
TL;DR: The majority of small enhancing renal masses grow at a slow rate when observed and serial radiographic data alone are insufficient to predict the true natural history of these lesions, so physicians and patients assume a calculated risk when following these tumors.

661 citations


Journal ArticleDOI
TL;DR: The results of this large, contemporary, multi-institutional series show that radical cystectomy and pelvic lymphadenectomy provide durable local control and disease specific survival in patients with localized invasive transitional cell carcinoma.

643 citations


Journal ArticleDOI
TL;DR: In this paper, the authors compared the cancer detection rates and complications of different extended prostate biopsy (greater than 6 cores) schemes for diagnostic evaluation in men scheduled for biopsy to identify the optimal scheme.

448 citations


Journal ArticleDOI
TL;DR: These long-term results confirm the previous observations regarding the safety of high dose intensity modulated radiation therapy for clinically localized prostate cancer and the increased conformality of the dose distribution associated with intensity modulation radiation therapy.

447 citations


Journal ArticleDOI
TL;DR: The ICIQ can offer a full range of urinary tract symptom questionnaires and the development of the ICIQ website is anticipated to be crucial for informing potential users of the phase of development of all ICIQ modules.

397 citations


Journal ArticleDOI
TL;DR: A further reduction in cigarette smoking, and a decrease in the rates of obesity and hypertension would likely moderate the increasing incidence of renal cell cancer.

391 citations


Journal ArticleDOI
TL;DR: It is critical for urologists to distinguish between a diagnosis of HGPIN and that of atypical foci suspicious for cancer on needle biopsy, as these 2 entities indicate different risks of carcinoma on re-biopsy and different recommendations for followup.

Journal ArticleDOI
TL;DR: Pre-biopsy pelvic phased array dynamic contrast enhanced magnetic resonance imaging is an accurate technique for detecting and quantifying intracapsular transition or peripheral zone tumor foci greater than 0.2 cc and has promising implications for cancer detection, prognosis and treatment.

Journal ArticleDOI
TL;DR: The stratification in three main renal cell carcinoma histologic subtypes as defined by the 1997 UICC-American Joint Committee on Cancer consensus should not be considered a major prognostic variable comparable to TNM stage, Fuhrman grade and ECOG PS.

Journal ArticleDOI
TL;DR: Ileal orthotopic bladder substitution combined with an afferent ileal tubular segment allows for good long-term functional results provided patients are restrictively selected, postoperative instructions are followed carefully, and typical complications such as outlet obstruction and hernias are treated early.

Journal ArticleDOI
TL;DR: The aggressive potential of small renal cell carcinoma increases dramatically beyond a tumor diameter of 3 cm, given the difficulty in measuring tumor diameters reliably with sequential imaging studies, the threshold for selecting patients for a surveillance strategy should be set well under this parameter.

Journal ArticleDOI
TL;DR: This pulsed cavitational ultrasound system is capable of transcutaneous nonthermal destruction of renal tissue and Refinement of this technology for noninvasive ablation of small renal masses is currently under way.

Journal ArticleDOI
TL;DR: Endoscopic treatment provides a high rate of success in children with reflux that decreases with increasing grade, although multiple treatments may be necessary, and future reports of endoscopic therapy should include rates of urinary tract infection and renal scarring.

Journal ArticleDOI
TL;DR: RALP showed advantages of decreased hospital stay, decreased narcotic use and operative times approaching those of open surgery, and as robotic technology improves, this method of repair may become the minimally invasive treatment of choice.

Journal ArticleDOI
TL;DR: A minority of men experienced improvement in penile abnormality, while penile length decreased during the 1-year followup, in what is the largest study to explore the natural history of PD.

Journal ArticleDOI
TL;DR: The SEER registry was used to characterize national practice patterns for the surgical management of small renal masses to identify a possible quality of care concern that should be addressed by the urological community.

Journal ArticleDOI
TL;DR: A modification of the Walsh RRP is described that overcomes caudal retraction, reconstructs the posterior fibrous raphe and decreases time to continence and careful reconstruction of the posterior aspect of the rhabdosphincter markedly shortens time toContinence.

Journal ArticleDOI
TL;DR: Nationally renal tumor size at presentation has steadily and consistently decreased, and patients more recently diagnosed had improved survival, which could be attributable to decreased tumor size in the latter cohorts.

Journal ArticleDOI
TL;DR: Prostate cancers identified in a screening setting have a substantially higher likelihood of being indolent than those predicted by a previously proposed nomogram, however, an updated model can support patients and clinicians when the various treatment options for prostate cancer are considered.

Journal ArticleDOI
TL;DR: The bladder is a better and more reliable witness in men than in women with a greater correlation between OAB symptoms and urodynamic DO, more so in the OAB wet than in OAB dry patients.

Journal ArticleDOI
TL;DR: Reducing the risk of erectile dysfunction may be a useful and to this point unexploited motivation for men to engage in health promoting behaviors, and physical activity was inversely associated with therisk of erectiles dysfunction developing.

Journal ArticleDOI
TL;DR: At 19 years of followup SWL for renal and proximal ureteral stones was associated with the development of hypertension and diabetes mellitus, and the incidence of these conditions was significantly higher than in a cohort of conservatively treated patients with nephrolithiasis.

Journal ArticleDOI
TL;DR: Tolterodine did not adversely affect urinary function in men with OAB and BOO, and there was no evidence of clinically meaningful changes in voiding pressure and PVR or urinary retention.

Journal ArticleDOI
TL;DR: Evidence indicating that SNS is effective for decreasing symptoms in patients with urge incontinence is shown, with evidence indicating that about 80% achieved continence or greater than 50% improvement in their mainincontinence symptoms after SNS.

Journal ArticleDOI
TL;DR: The results show that intradetrusor botulinum-A toxin injections may be an efficient and safe treatment option in patients with severe overactive bladder resistant to all conventional treatments.

Journal ArticleDOI
TL;DR: Prevalence of urinary incontinence in women in the United States is high, and varies with age, race/ethnicity and socioeconomic variables.