J
John Turton
Researcher at University College London
Publications - 67
Citations - 2194
John Turton is an academic researcher from University College London. The author has contributed to research in topics: Bone marrow & Niosome. The author has an hindex of 26, co-authored 67 publications receiving 2089 citations. Previous affiliations of John Turton include University of London.
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Journal ArticleDOI
Dynamic Imaging of Functionalized Multi‐Walled Carbon Nanotube Systemic Circulation and Urinary Excretion
Lara Lacerda,Anuradha Soundararajan,Ravi Singh,Giorgia Pastorin,Khuloud T. Al-Jamal,John Turton,Peter M. Frederik,María Antonia Herrero,Shouping Li,Ande Bao,Dimitris Emfietzoglou,Stephen J. Mather,William T. Phillips,Maurizio Prato,Alberto Bianco,Beth A. Goins,Kostas Kostarelos +16 more
TL;DR: Imaging showed that nanotubes enter the systemic blood circulation and within 5 min begin to permeate through the renal glomerular filtration system into the bladder.
Journal ArticleDOI
Markers of experimental acute inflammation in the Wistar Han rat with particular reference to haptoglobin and C-reactive protein.
Paul Giffen,John Turton,C. M. Andrews,C. M. Andrews,P. Barrett,Christopher J.P. Clarke,K.-W. Fung,Michael R. Munday,Ian Roman,Rosemary Smyth,K. Walshe,Malcolm York +11 more
TL;DR: It is concluded that serum CRP is a poor marker of acute inflammation in the rat in comparison with serum Hp and plasma Fbgn, while serum HP is shown to be the most sensitive and useful marker of acutely inflammation.
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Investigations into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats
TL;DR: It is suggested that urinary taurine and possibly creatine may be useful markers of liver injury and dysfunction and partly due to changes in protein synthesis and hence in sulphur amino acid metabolism caused by hepatotoxic agents.
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Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols.
Kersti Karu,Martin Hornshaw,Gary Woffendin,Karl Bodin,Mats Hamberg,Gunvor Alvelius,Jan Sjövall,John Turton,Yuqin Wang,William J. Griffiths +9 more
TL;DR: A novel liquid chromatography (LC) multi-stage fragmentation mass spectrometry (MSn) methodology for the identification, with high sensitivity (low pg), of cholesterol metabolites in rat brain was described.
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Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse.
TL;DR: Modest tumour targeting was achieved by the delivery of doxorubicin in sorbitan monostearate niosomes, increasing the tumour to heart AUC0–24 ratio from 0.27 to 0.36 and a doubling of tumoricidal activity.