John W. Hotra

TL;DR: The transcriptome of fetal membranes after spontaneous rupture of membranes in term labor is characterized by region- and tissue-specific differential expression of genes that are involved in signature pathways, which include extracellular matrix-receptor interactions.

TL;DR: Placental galectin-1 expression is higher in severe PE than in normal pregnancy regardless of the presence of SGA, and the protein is abundantly present in third trimester human placentas, suggesting it may be implicated in maternal–fetal immune tolerance in humans.

TL;DR: Parsimony- and codon model-based phylogenetic analysis of coding sequences show that amino acid replacements occurred in early mammalian evolution on key residues, including gain of cysteines, which regulate immune functions by redox status-mediated conformational changes that disable sugar binding and dimerization, and that the acquired immunoregulatory functions of galectin-1 then became highly conserved in eutherian lineages.

TL;DR: To assess the effects of omega-3 FA excess and deficiency during pregnancy and lactation on the offspring's neural transmission as evidenced by their auditory brainstem responses (ABR), female Wistar rats were given one of three diets from day 1 of pregnancy through lactation.

TL;DR: Omega-3 FA over-nutrition or imbalance during pregnancy and lactation had adverse effects on life span and sensory/neurological function in old adulthood.