Yu Mi Han

TL;DR: For the first time, increased expression of specific placental miRNAs is reported in preeclampsia with and without SGA, providing novel targets for further investigation of the pathophysiology of preeClampsia.

TL;DR: Parsimony- and codon model-based phylogenetic analysis of coding sequences show that amino acid replacements occurred in early mammalian evolution on key residues, including gain of cysteines, which regulate immune functions by redox status-mediated conformational changes that disable sugar binding and dimerization, and that the acquired immunoregulatory functions of galectin-1 then became highly conserved in eutherian lineages.

TL;DR: It is reported that the anatomical region has a substantial impact on the transcriptional program and the biological properties of the amnion, including Labor-associated switching to a proinflammatory signature is a feature particular to placental amnions.

TL;DR: It is suggested that PPROM is associated with specific changes in the hemostatic/coagulation system and median plasma concentrations of tissue factor and TFPI are higher than in women with normal pregnancies.

TL;DR: Galectin-1 mRNA and protein were detected in amniotic epithelium, chorioamniotic mesodermal cells, and decidual stromal cells.