J
Joaquin Santolaya-Forgas
Researcher at Rutgers University
Publications - 53
Citations - 1099
Joaquin Santolaya-Forgas is an academic researcher from Rutgers University. The author has contributed to research in topics: Pregnancy & Umbilical cord. The author has an hindex of 16, co-authored 52 publications receiving 985 citations. Previous affiliations of Joaquin Santolaya-Forgas include Texas Tech University & Wayne State University.
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Journal ArticleDOI
A primate subfamily of galectins expressed at the maternal–fetal interface that promote immune cell death
Nandor Gabor Than,Roberto Romero,Morris Goodman,Amy Weckle,Jun Xing,Zhong Dong,Yi Xu,Federica Tarquini,András Szilágyi,Péter Gál,Zhuo-Cheng Hou,Adi L. Tarca,Chong Jai Kim,Chong Jai Kim,Jung Sun Kim,Jung Sun Kim,Saied Haidarian,Monica Uddin,Hans Bohn,Kurt Benirschke,Joaquin Santolaya-Forgas,Lawrence I. Grossman,Offer Erez,Sonia S. Hassan,Péter Závodszky,Zoltán Papp,Derek E. Wildman +26 more
TL;DR: It is proposed that placenta-specific galectins reduce the danger of maternal immune attacks on the fetal semiallograft, presumably conferring additional immune tolerance mechanisms and in turn sustaining hemochorial placentation during the long gestation of anthropoid primates.
Journal ArticleDOI
Middle cerebral artery peak systolic velocity: a new Doppler parameter in the assessment of growth-restricted fetuses.
Giancarlo Mari,Farhan Hanif,Michael Kruger,Erich Cosmi,Joaquin Santolaya-Forgas,Marjorie C. Treadwell +5 more
TL;DR: The hypothesis that MCA‐PSV can provide additional information on the prognosis of hypoxemic IUGR fetuses is tested.
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Human beta-defensin-2: a natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity.
Eleazar Soto,Jimmy Espinoza,Jyh Kae Nien,Juan Pedro Kusanovic,Offer Erez,Karina Richani,Joaquin Santolaya-Forgas,Roberto Romero +7 more
TL;DR: It is proposed that amniotic fluid HBD-2 is part of the innate immune system within theAmniotic cavity, and this may account for some of the antimicrobial activity of amniotics fluid.
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A New Approach to Fetal Echocardiography Digital Casts of the Fetal Cardiac Chambers and Great Vessels for Detection of Congenital Heart Disease
Luís F. Gonçalves,Luís F. Gonçalves,Jimmy Espinoza,Jimmy Espinoza,Wesley Lee,Wesley Lee,Jyh Kae Nien,Joon Seok Hong,Joaquin Santolaya-Forgas,Joaquin Santolaya-Forgas,Moshe Mazor,Roberto Romero,Roberto Romero +12 more
TL;DR: A method of 4‐dimensional reconstruction of the cardiac chambers and outflow tracts using a combination of spatiotemporal image correlation, “inversion mode,” and “B‐flow” imaging is described.
Journal ArticleDOI
Emergence of hormonal and redox regulation of galectin-1 in placental mammals: Implication in maternal–fetal immune tolerance
Nandor Gabor Than,Roberto Romero,Roberto Romero,Offer Erez,Offer Erez,Amy Weckle,Adi L. Tarca,John W. Hotra,Asad Abbas,Yu Mi Han,Sung Su Kim,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Francesca Gotsch,Zhuo-Cheng Hou,Joaquin Santolaya-Forgas,Kurt Benirschke,Zoltán Papp,Lawrence I. Grossman,Morris Goodman,Derek E. Wildman,Derek E. Wildman +21 more
TL;DR: Parsimony- and codon model-based phylogenetic analysis of coding sequences show that amino acid replacements occurred in early mammalian evolution on key residues, including gain of cysteines, which regulate immune functions by redox status-mediated conformational changes that disable sugar binding and dimerization, and that the acquired immunoregulatory functions of galectin-1 then became highly conserved in eutherian lineages.