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Joaquin Santolaya-Forgas

Researcher at Rutgers University

Publications -  53
Citations -  1099

Joaquin Santolaya-Forgas is an academic researcher from Rutgers University. The author has contributed to research in topics: Pregnancy & Umbilical cord. The author has an hindex of 16, co-authored 52 publications receiving 985 citations. Previous affiliations of Joaquin Santolaya-Forgas include Texas Tech University & Wayne State University.

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Human beta-defensin-2: a natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity.

TL;DR: It is proposed that amniotic fluid HBD-2 is part of the innate immune system within theAmniotic cavity, and this may account for some of the antimicrobial activity of amniotics fluid.
Journal ArticleDOI

Emergence of hormonal and redox regulation of galectin-1 in placental mammals: Implication in maternal–fetal immune tolerance

TL;DR: Parsimony- and codon model-based phylogenetic analysis of coding sequences show that amino acid replacements occurred in early mammalian evolution on key residues, including gain of cysteines, which regulate immune functions by redox status-mediated conformational changes that disable sugar binding and dimerization, and that the acquired immunoregulatory functions of galectin-1 then became highly conserved in eutherian lineages.