J
John Wade
Researcher at Ulster University
Publications - 34
Citations - 795
John Wade is an academic researcher from Ulster University. The author has contributed to research in topics: Spiking neural network & Neurotransmission. The author has an hindex of 12, co-authored 33 publications receiving 648 citations. Previous affiliations of John Wade include Nottingham Trent University & Intel.
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Journal ArticleDOI
SWAT: A Spiking Neural Network Training Algorithm for Classification Problems
TL;DR: A synaptic weight association training (SWAT) algorithm for spiking neural networks (SNNs) that merges the Bienenstock-Cooper-Munro (BCM) learning rule with spike timing dependent plasticity (STDP) and yields a unimodal weight distribution.
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Bidirectional Coupling between Astrocytes and Neurons Mediates Learning and Dynamic Coordination in the Brain: A Multiple Modeling Approach
TL;DR: Results show that slow inward currents cause synchronized postsynaptic activity in remote neurons and subsequently allow Spike-Timing-Dependent Plasticity based learning to occur at the associated synapses, and that bidirectional communication between neurons and astrocytes underpins dynamic coordination between neuron clusters.
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Potassium and sodium microdomains in thin astroglial processes: A computational model study
Kevin Breslin,John Wade,KongFatt Wong-Lin,Jim Harkin,Bronac Flanagan,Harm van Zalinge,Steve Hall,Matthew C. Walker,Alexei Verkhratsky,Alexei Verkhratsky,Liam McDaid +10 more
TL;DR: A multi-compartmental mathematical model is developed which proposes a novel mechanism whereby the flow of cations in thin processes is restricted due to negatively charged membrane lipids which result in the formation of deep potential wells near the dipole heads.
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Self-repair in a bidirectionally coupled astrocyte-neuron (AN) system based on retrograde signaling.
TL;DR: This model of self-repair is based on recent research showing that retrograde signaling via astrocytes can increase the PR of neurotransmitter release at damaged or low transmission PR synapses and provides a biologically inspired basis for developing highly adaptive, distributed computing systems that can self- repair autonomously without the traditional constraint of a central fault detect/repair unit.
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SPANNER: A Self-Repairing Spiking Neural Network Hardware Architecture
TL;DR: This paper demonstrates that the hardware can self-detect and self-repair synaptic faults without the conventional components for the fault detection and fault repairing.