John Welsh

TL;DR: This principle is demonstrated by using two oligos, alone and together, to generate three sets of fingerprints and map thirteen polymorphisms in the C57BL/6J x DBA/2J set of recombinant inbred mice.

TL;DR: Using genomic fingerprinting by an arbitrarily primed polymerase chain reaction, a collection of Eurasian and North American isolates of spirochetes that are generally categorized as B. burgdorferi are resolved into three groups.

TL;DR: From a systems perspective, platelet accumulation produces an altered microenvironment that shapes thrombus architecture, which in turn affects agonist distribution and subsequent thrombin accumulation and growth of the core.

TL;DR: It is demonstrated that in addition to the activation state of individual platelets, the physical properties of the accumulated mass of adherent platelets is critical in determining intrathrombus agonist distribution and platelet activation and a novel role for integrin signaling is defined in the regulation of intrathrubus transport rates and localization of thrombin activity.

TL;DR: It is concluded that Vav3 mediates RPTK signaling and regulates GTPase activity, its native and mutant forms are able to modulate cell morphology, and it has the potential to induce cell transformation.