J
Johnathan Furr
Researcher at Southern Research Institute
Publications - 60
Citations - 5884
Johnathan Furr is an academic researcher from Southern Research Institute. The author has contributed to research in topics: Phthalate & Androgen. The author has an hindex of 32, co-authored 59 publications receiving 5491 citations. Previous affiliations of Johnathan Furr include United States Environmental Protection Agency & Research Triangle Park.
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Journal ArticleDOI
Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.
L. Earl Gray,Joseph S. Ostby,Johnathan Furr,Matthew Price,D.N. Rao Veeramachaneni,Louise G. Parks +5 more
TL;DR: It is hypothesized that the phthalate esters that altered testis function in the pubertal male rat would also alter testisfunction in the fetal male and produce malformations of androgen-dependent tissues and, in summary, DEHP, BBP, and DINP all altered sexual differentiation, whereas DOTP, DEP, or DMP were ineffective at this dose.
Journal ArticleDOI
Effects of environmental antiandrogens on reproductive development in experimental animals
Gray Le,Joseph S. Ostby,Johnathan Furr,Cynthia J. Wolf,Christy S. Lambright,L. Parks,D. N. Veeramachaneni,Vickie S. Wilson,Matthew Price,Andrew K. Hotchkiss,Edward F. Orlando,Louis J. Guillette +11 more
TL;DR: In this paper, the authors measured fetal tissue concentrations of 10-20 p.p.t.m. of the DDT metabolite, p,p'-DDE, are correlated with reproductive malformations in male offspring.
Journal ArticleDOI
A Mixture of Five Phthalate Esters Inhibits Fetal Testicular Testosterone Production in the Sprague-Dawley Rat in a Cumulative, Dose-Additive Manner
Kembra L. Howdeshell,Vickie S. Wilson,Johnathan Furr,Christy R. Lambright,Cynthia V. Rider,Chad R. Blystone,Andrew K. Hotchkiss,Leon Earl Gray +7 more
TL;DR: In this article, the authors characterized the dose-response effects of six individual phthalates (BBP, DBP, DEHP, diethyl hexyl phthalate [DEP], DiBP, DiBP and Dipentyl Phthalate (DPP) on testicular testosterone production following exposure of Sprague-Dawley rats on GD 8-18.
production in the Sprague Dawley rat in a cumulative, dose additive manner.
Kembra L. Howdeshell,Vickie S. Wilson,Johnathan Furr,Christy R. Lambright,V Cynthia,Chad R. Blystone,Andrew K. Hotchkiss,Leon Earl Gray +7 more
TL;DR: It is demonstrated that individual phthalates with a similar mechanism of action can elicit cumulative, dose additive effects on fetal testosterone production and pregnancy when administered as a mixture.
Journal ArticleDOI
Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals1
L. Earl Gray,Vickie S. Wilson,Tammy E. Stoker,Christy S. Lambright,Johnathan Furr,Nigel Noriega,Kembra L. Howdeshell,Gerald T. Ankley,Louis J. Guillette +8 more
TL;DR: Information is presented on the classes of environmental chemicals that display antiandrogenic and androgenic activities in vitro and in vivo and an insight into how exposure to mixtures these chemicals might behave in utero is provided.