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Jolanta Myśliwska

Researcher at Gdańsk Medical University

Publications -  110
Citations -  4226

Jolanta Myśliwska is an academic researcher from Gdańsk Medical University. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 30, co-authored 110 publications receiving 3863 citations.

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First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells.

TL;DR: The therapy allowed for significant alleviation of the symptoms and reduction of pharmacologic immunosuppression in the case of chronic GvHD, while in the cases of grade IV acute Gv HD it only transiently improved the condition, for the longest time within all Immunosuppressants used nonetheless.
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Administration of CD4+CD25highCD127− Regulatory T Cells Preserves β-Cell Function in Type 1 Diabetes in Children

TL;DR: It is shown for the first time that the infusion of autologous Tregs prolongs remission in recently diagnosed type 1 diabetes in children and is safe and tolerable in children with recent-onset type 2 diabetes.
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Effects of intranasal 17beta-estradiol administration on serum bioactive interleukin-6 and C-reactive protein levels in healthy postmenopausal women.

TL;DR: The results of this study show that intranasal, similarly to transdermal, E2 administration does not increase serum CRP levels in postmenopausal women, and support the hypothesis that CRP increase during oral estrogen treatment is not mediated by the enhancement of interleukin-6 production by the immune cells but is rather caused by the hepatic first-pass metabolism effect.
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CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction.

TL;DR: Treg were able to inhibit both T CD8+ and NK lymphocyte cytotoxic activities in a direct cell-to-cell interaction, while the mechanism underlying a decrease in NK cytotoxicity remained unclear.