Jon Hill

TL;DR: Kidney compartment–specific eQTL analysis goes beyond GWAS to reveal causal genes and pathways involved in renal disease development, and reduces Dab2 expression in renal tubules protected mice from CKD.

TL;DR: By reviewing how current and past successes have been accomplished along with the data used, important stratagems emerge that can provide a wealth of ideas for novel workflows, as well as provide a guide for future discoveries.

TL;DR: In American Indians with type 2 diabetes and preserved GFR at baseline, increasing ACR reflects the progression of earlier structural glomerular lesions, whereas early GFR decline may not accurately reflect such lesions.

TL;DR: This review seeks to provide new insight on emerging clinical candidates under investigation for the treatment of diabetic nephropathy, the largest non-communicable cause of death worldwide.

TL;DR: In this paper, the authors investigated the molecular mechanisms of NAFLD and fibrosis using total RNA-Seq and identified gene expression clusters that strongly correlate with fibrosis stage including four genes that have been found consistently across previously published transcriptomic studies on NASH i.e. COL1A2, EFEMP2, FBLN5 and THBS2.