Viji Nair

TL;DR: The authors demonstrated that the amount of EGF in the urine is just as useful, providing a biomarker that can be easily tracked over time without requiring invasive biopsies, and identified uEGF as an independent risk predictor of CKD progression.

TL;DR: These findings provide strong evidence that KRIS proteins contribute to the inflammatory process underlying end-stage renal disease development in both types of diabetes, and point to new therapeutic targets and new prognostic tests to identify subjects at risk of end-Stage renal disease.

TL;DR: The first genome-scale method to identify genes with cell-lineage-specific expression, even in lineages not separable by experimental microdissection is developed, which identified genes implicated as causal in hereditary glomerular disease and involved in molecular pathways of acquired and chronic renal diseases.

TL;DR: Tissue-specific changes in metabolism in complication-prone tissues in diabetes are highlighted and it is suggested that urinary TCA cycle intermediates are potential prognostic biomarkers of diabetic kidney disease progression.

TL;DR: The human–mouse shared glomerular transcriptional networks will assist DN researchers in selecting mouse models most relevant to the human disease process of interest and allow identification of new pathways shared between mice and humans.