J
Jonathan P.S. Knisely
Researcher at Cornell University
Publications - 205
Citations - 6240
Jonathan P.S. Knisely is an academic researcher from Cornell University. The author has contributed to research in topics: Radiosurgery & Radiation therapy. The author has an hindex of 33, co-authored 180 publications receiving 5361 citations. Previous affiliations of Jonathan P.S. Knisely include Johns Hopkins University & North Shore-LIJ Health System.
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Journal ArticleDOI
Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases
Paul W. Sperduto,Norbert Kased,David Roberge,Zhiyuan Xu,Ryan Shanley,Xianghua Luo,Penny K. Sneed,Samuel T. Chao,Robert J. Weil,John H. Suh,Amit Bhatt,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Nan Lin,Minesh P. Mehta +21 more
TL;DR: These indices and related worksheet provide an accurate and facile diagnosis-specific tool to estimate survival, potentially select appropriate treatment, and stratify clinical trials for patients with brain metastases.
Journal ArticleDOI
Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients
Paul W. Sperduto,Samuel T. Chao,Penny K. Sneed,Xianghua Luo,John H. Suh,David Roberge,Amit Bhatt,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Amanda L. Schwer,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Minesh P. Mehta +17 more
TL;DR: The prognostic factors for BM patients varied by diagnosis, and two new DS-GPA indexes were designed for breast/gastrointestinal cancer and melanoma/renal cell carcinoma.
Journal ArticleDOI
Effect of Tumor Subtype on Survival and the Graded Prognostic Assessment for Patients With Breast Cancer and Brain Metastases
Paul W. Sperduto,Norbert Kased,David Roberge,Zhiyuan Xu,Ryan Shanley,Xianghua Luo,Penny K. Sneed,Samuel T. Chao,Robert J. Weil,John H. Suh,Amit Bhatt,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Nan Lin,Minesh P. Mehta +21 more
TL;DR: The Breast-GPA documents wide variation in prognosis and shows clear separation between subgroups of patients with breast cancer and brain metastases and this tool will aid clinical decision making and stratification in clinical trials.
Journal ArticleDOI
Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival
Jonathan P.S. Knisely,James B. Yu,Jaclyn C. Flanigan,Mario Sznol,Harriet M. Kluger,Veronica Chiang,Veronica Chiang +6 more
TL;DR: The survival of patients with melanoma brain metastases managed with ipilimumab and definitive radiosurgery can exceed the commonly anticipated 4-6 months, even after adjustment for performance status without an increased need for salvage WBRT.
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Phase II Trial of Radiosurgery for One to Three Newly Diagnosed Brain Metastases From Renal Cell Carcinoma, Melanoma, and Sarcoma: An Eastern Cooperative Oncology Group Study (E 6397)
Rafael Manon,Anne O'Neill,Jonathan P.S. Knisely,Maria Werner-Wasik,Hillard M. Lazarus,Henry N. Wagner,Mark R. Gilbert,Minesh P. Mehta +7 more
TL;DR: Delaying W BRT may be appropriate for some subgroups of patients with radioresistant tumors, but routine avoidance of WBRT should be approached judiciously.