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Christina Maria Sperduto
Researcher at Dartmouth College
Publications - 9
Citations - 2665
Christina Maria Sperduto is an academic researcher from Dartmouth College. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 6, co-authored 9 publications receiving 2299 citations. Previous affiliations of Christina Maria Sperduto include University of Minnesota.
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Journal ArticleDOI
Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases
Paul W. Sperduto,Norbert Kased,David Roberge,Zhiyuan Xu,Ryan Shanley,Xianghua Luo,Penny K. Sneed,Samuel T. Chao,Robert J. Weil,John H. Suh,Amit Bhatt,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Nan Lin,Minesh P. Mehta +21 more
TL;DR: These indices and related worksheet provide an accurate and facile diagnosis-specific tool to estimate survival, potentially select appropriate treatment, and stratify clinical trials for patients with brain metastases.
Journal ArticleDOI
Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients
Paul W. Sperduto,Samuel T. Chao,Penny K. Sneed,Xianghua Luo,John H. Suh,David Roberge,Amit Bhatt,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Amanda L. Schwer,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Minesh P. Mehta +17 more
TL;DR: The prognostic factors for BM patients varied by diagnosis, and two new DS-GPA indexes were designed for breast/gastrointestinal cancer and melanoma/renal cell carcinoma.
Journal ArticleDOI
Effect of Tumor Subtype on Survival and the Graded Prognostic Assessment for Patients With Breast Cancer and Brain Metastases
Paul W. Sperduto,Norbert Kased,David Roberge,Zhiyuan Xu,Ryan Shanley,Xianghua Luo,Penny K. Sneed,Samuel T. Chao,Robert J. Weil,John H. Suh,Amit Bhatt,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Nan Lin,Minesh P. Mehta +21 more
TL;DR: The Breast-GPA documents wide variation in prognosis and shows clear separation between subgroups of patients with breast cancer and brain metastases and this tool will aid clinical decision making and stratification in clinical trials.
Journal ArticleDOI
The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer.
Paul W. Sperduto,Norbert Kased,David Roberge,Samuel T. Chao,Ryan Shanley,Xianghua Luo,Penny K. Sneed,Penny K. Sneed,John H. Suh,Robert J. Weil,Ashley W. Jensen,Paul D. Brown,Helen A. Shih,John P. Kirkpatrick,Laurie E. Gaspar,John B. Fiveash,Veronica Chiang,Jonathan P.S. Knisely,Christina Maria Sperduto,Nan Lin,Minesh P. Mehta +20 more
TL;DR: The relationship of breast cancer subtype to the time interval from primary diagnosis to development of BM, number of BM at initial BM presentation and survival is investigated to determine if screening brain MRIs are indicated in patients with Basal or HER2 subtypes.
Journal ArticleDOI
A validation study of a new prognostic index for patients with brain metastases: the Graded Prognostic Assessment.
Christina Maria Sperduto,Yoichi Watanabe,John C. Mullan,Terry Hood,Gregg N. Dyste,Charles R. Watts,Gail Papermaster Bender,Paul W. Sperduto +7 more
TL;DR: The University of Minnesota data correlate well with the RTOG data and validate the use of the GPA as an effective prognostic index for patients with brain metastases, which appears to be as prognostic as the RPA.