J
Jonathan Peter
Researcher at University of Cape Town
Publications - 53
Citations - 1995
Jonathan Peter is an academic researcher from University of Cape Town. The author has contributed to research in topics: Tuberculosis & Tuberculosis diagnosis. The author has an hindex of 21, co-authored 49 publications receiving 1546 citations. Previous affiliations of Jonathan Peter include University of Oxford & Groote Schuur Hospital.
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Journal ArticleDOI
Point-of-care diagnosis of tuberculosis: past, present and future.
TL;DR: The accuracy and potential impact of established and newer potential POC diagnostic tests for TB, including smear microscopy, the Xpert MTB/RIF assay (Cepheid) and the Determine TB lipoarabinomannan antigen test (Alere) are reviewed.
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The Utility of High-Flow Nasal Oxygen for Severe COVID-19 Pneumonia in a Resource-Constrained Setting: A Multi-Centre Prospective Observational Study
G Calligaro,U Lalla,Gordon Audley,Phindile Gina,Malcolm Miller,Marc Mendelson,Sipho Dlamini,Sean Wasserman,Graeme Meintjes,Jonathan Peter,Dion A Levin,Joel A. Dave,Ntobeko A B Ntusi,Stuart Meier,Francesca Little,Desiree L. Moodley,E H Louw,Andre Nortje,Arifa Parker,Jantjie Taljaard,Brian W. Allwood,Keertan Dheda,Keertan Dheda,Coenraad F.N. Koegelenberg +23 more
TL;DR: In a resource-constrained setting, HFNO for severe COVID-19 HRF is feasible and more almost half of those who receive it can be successfully weaned without the need for mechanical ventilation.
Journal ArticleDOI
Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples
Keertan Dheda,Keertan Dheda,Virginia Davids,Laura Lenders,Teri Roberts,Richard Meldau,Daphne I. Ling,Laurence Brunet,Richard van Zyl Smit,Jonathan Peter,Clare Green,Motasim Badri,Leonardo Antonio Sechi,Surendra K. Sharma,Michael Hoelscher,Rodney Dawson,Andrew Whitelaw,Jonathan M. Blackburn,Madhukar Pai,Alimuddin Zumla +19 more
TL;DR: The preliminary data indicate that in a high burden primary care setting the diagnostic usefulness of urine-LAM is limited, as a rule-in test, to a specific patient subgroup i.e. smear-negative HIV-infected TB patients with a CD4 count <200 cells/mm3, who would otherwise have required further investigation.
Journal ArticleDOI
Diagnostic accuracy of a urine lipoarabinomannan strip-test for TB detection in HIV-infected hospitalised patients.
Jonathan Peter,Grant Theron,Richard N. van Zyl-Smit,Asheen Haripersad,L. Mottay,Sarah Kraus,Anke Binder,Richard Meldau,Anneli Hardy,Keertan Dheda,Keertan Dheda +10 more
TL;DR: It is indicated that the LAM strip-test may be a potentially useful rapid rule-in test for TB in hospitalised patients with advanced immunosuppression and the grade 2, but not the manufacturer-recommended grade 1 cut-off point, offered superior rule- in utility and inter-reader reliability.
Journal ArticleDOI
Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments.
TL;DR: Urine LAM currently offers little utility for the diagnosis of tuberculosis in unselected populations, however, urine LAM appears promising as a diagnostic tool in HIV-infected patients with CD4 cell counts less than 200 cells/μl in different clinical settings.