Jonghye Choi

TL;DR: In rats injected iv with 30 mg/kg, mitotic figures in hepatocytes were significantly increased and multifocal acute injuries with dark brown pigment were noted in lungs, while no significant damage was observed in rats treated orally with the same dosage.

TL;DR: Toxicity endpoints of reproduction/developmental screening test including mating, fertility, implantation, delivery and foetus were measured and there was no evidence of toxicity.

TL;DR: It is suggested that the possible transfer of silver nanoparticles from pregnant dams to the fetus through mainly placenta through mainly Placenta is suggested.

TL;DR: The findings provide the evidence that zinc oxide nanoparticles, titanium oxide nanoparticle and their mixture are ‘non corrosive’ and ‘ non-irritant’ to the human skin by a globally harmonized classification system.

TL;DR: The effects of zinc oxide nanoparticles on dams and fetuses were investigated in rats after intravenous injection from gestation day 6 to 20 and lowest observed adverse effect level of injection route was suggested to be 5 mg/kg in dams and no observed adverse effects level was suggested in fetal developmental toxicity.