Joon-Sung Park

TL;DR: In this article , the authors describe a general solution to this problem that starts with a broad exploration of the vast space of possible binding modes to a selected region of a protein surface and then intensifies the search in the vicinity of the most promising binding modes.

TL;DR: The results suggest that WhcE functions as a transcription factor which can activate the trxB gene, as well as other genes, possibly by sensing redox changes during the metabolic downshifting of cells from exponential growth to the stationary phase, whereas sigmaH appears to function as the sigma factor for these genes, including whcE.

TL;DR: Data indicate that the sigH gene of C. glutamicum stimulates and regulates its own expression in the stationary growth phase in response to environmental stimuli, and participates in the expression of other genes which are important for survival following heat and oxidative stress response.

TL;DR: The result suggests that the Corynebacterial clone may encode proteins that prevent the cells from accumulating the chromogenic compound, X-gal, and may express repressor-like proteins for the genes.