Joonsung Hwang

TL;DR: It is suggested that only a limited number of protein changes occur in multidrug-resistant cell lines, which are associated with a loss of translatable mRNA for these proteins.

TL;DR: The demonstration of high levels of the P-95 protein in clinical samples obtained from patients refractory to Adr suggests that this protein may play a role in clinical drug resistance.

TL;DR: The central role of Dlx3 is demonstrated as a crucial transcriptional regulator of hair formation and regeneration and the results establish that DlX3 is essential for hair morphogenesis, differentiation and cycling programs.

TL;DR: It is found that dentin sialophosphoprotein (Dspp), a major component of the dentin matrix, is strongly down-regulated in odontoblasts lacking Dlx3, establishing a regulatory pathway where the transcription factor DlX3 is essential in dentin formation by directly regulating a crucial matrix protein.

TL;DR: Dlx3 ablation in epidermis is linked to altered epidermal differentiation, barrier development, and IL-17–associated skin inflammation and this model provides a platform that will allow the systematic exploration of the contributions of keratinocytes to cutaneous inflammation.