M
Mark C. Udey
Researcher at Washington University in St. Louis
Publications - 121
Citations - 9097
Mark C. Udey is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Langerhans cell & Dendritic cell. The author has an hindex of 46, co-authored 117 publications receiving 8591 citations. Previous affiliations of Mark C. Udey include National Institutes of Health.
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Journal ArticleDOI
Characterization and isolation of stem cell–enriched human hair follicle bulge cells
Manabu Ohyama,Atsushi Terunuma,Christine L. Tock,Michael F. Radonovich,Cynthia A. Pise-Masison,Steven B. Hopping,John N. Brady,Mark C. Udey,Jonathan C. Vogel +8 more
TL;DR: The distribution of label-retaining cells is determined to define the human anagen bulge and CD200+ cells obtained from hair follicle suspensions demonstrated high colony-forming efficiency in clonogenic assays, indicating successful enrichment of living human bulge stem cells.
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The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure
Yasmine Belkaid,Karl F. Hoffmann,Susana Mendez,Shaden Kamhawi,Mark C. Udey,Tom A. Wynn,David L. Sacks +6 more
TL;DR: A novel therapeutic approach to eliminate latency, infection reservoirs, and the risk of reactivation disease is suggested as sterile cure was achieved in IL-10–deficient and IL-4/IL-10 double-deficient mice.
Journal Article
Activation of Cutaneous Dendritic Cells by CpG-Containing Oligodeoxynucleotides: A Role for Dendritic Cells in the Augmentation of Th1 Responses by Immunostimulatory DNA
TL;DR: It is concluded that immunostimulatory CpG ODN stimulate DC in vitro and in vivo and that bacterial DNA-based vaccines may preferentially elicit Th1-predominant immune responses because they activate and mobilize DC and induce them to produce large amounts of IL-12.
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Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin.
TL;DR: It is reported that fresh murine LC express cadherins, and that LC adhere to KC in vitro through E-cadherin, and to begin to elucidate mechanisms involved in LC trafficking, LC-keratinocyte (KC) interactions are characterized.
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A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells
TL;DR: It is concluded that endogenous TGF-β1 is essential for normal murine LC development or epidermal localization, and LC development is not simply delayed in these animals.