J
Jorge F. Vázquez-Castellanos
Researcher at Katholieke Universiteit Leuven
Publications - 28
Citations - 1142
Jorge F. Vázquez-Castellanos is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Gut flora & Medicine. The author has an hindex of 15, co-authored 24 publications receiving 798 citations. Previous affiliations of Jorge F. Vázquez-Castellanos include University of Valencia & National Autonomous University of Mexico.
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Journal ArticleDOI
Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals
Jorge F. Vázquez-Castellanos,Sergio Serrano-Villar,Amparo Latorre,Alejandro Artacho,María Loreto Ferrús,Nadia Madrid,A. Vallejo,Talia Sainz,Javier Martínez-Botas,Sara Ferrando-Martinez,Mar Vera,Fernando Dronda,Manuel Leal,J del Romero,Santiago Moreno,Vicente Estrada,María José Gosalbes,Andrés Moya +17 more
TL;DR: Systemic markers of innate and adaptive immunity in a cohort of HIV-infected individuals on successful antiretroviral therapy without comorbidities and in healthy non-HIV- infected subjects are determined.
Journal ArticleDOI
Study of the viral and microbial communities associated with Crohn's disease: a metagenomic approach.
Vicente Pérez-Brocal,Rodrigo García-López,Jorge F. Vázquez-Castellanos,Pilar Nos,Belén Beltrán,Amparo Latorre,Andrés Moya +6 more
TL;DR: The use of an extensive database is critical to retrieve more viral hits than in previous approaches, and a lower diversity but more variability between the CD samples in both virome and microbiome was found.
Journal ArticleDOI
The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects
Sergio Serrano-Villar,Jorge F. Vázquez-Castellanos,Alejandro Vallejo,Amparo Latorre,Talia Sainz,Sara Ferrando-Martinez,David Rojo,Javier Martínez-Botas,J del Romero,Nadia Madrid,Manuel Leal,Juana I. Mosele,Maria-José Motilva,Coral Barbas,Manuel Ferrer,Andrés Moya,Santiago Moreno,María José Gosalbes,Vicente Estrada +18 more
TL;DR: The short dietary supplementation attenuated HIV-associated dysbiosis, which was most apparent in VU individuals but less so in ART+ subjects, whose gut microbiota was found more resilient, and the bacterial butyrate synthesis pathway holds promise as a viable target for interventions.
Journal ArticleDOI
Fecal Microbiota Transplantation Reduces Symptoms in Some Patients With Irritable Bowel Syndrome With Predominant Abdominal Bloating: Short- and Long-term Results From a Placebo-Controlled Randomized Trial.
Tom Holvoet,Tom Holvoet,Marie Joossens,Jorge F. Vázquez-Castellanos,Evelien Christiaens,Lander Heyerick,Jerina Boelens,Bruno Verhasselt,Hans Van Vlierberghe,Martine De Vos,Jeroen Raes,Danny De Looze,Danny De Looze +12 more
TL;DR: In a randomized trial of patients with treatment-refractory IBS with predominant bloating, FMT relieved symptoms compared with placebo (autologous transplant), although effects decreased over 1 year.
Journal ArticleDOI
Gut Bacteria Metabolism Impacts Immune Recovery in HIV-infected Individuals.
Sergio Serrano-Villar,David Rojo,Mónica Martínez-Martínez,Simon Deusch,Jorge F. Vázquez-Castellanos,Rafael Bargiela,Talía Sainz,Mar Vera,Santiago Moreno,Vicente Estrada,María José Gosalbes,Amparo Latorre,Jana Seifert,Coral Barbas,Andrés Moya,Manuel Ferrer +15 more
TL;DR: It is found that HIV infection is associated to dramatic changes in the active set of gut bacteria simultaneously altering the metabolic outcomes, and reduced inflammation and immune recovery is a joint solution orchestrated by both the active fraction of the gut microbiota and the host.