S
Sara Ferrando-Martinez
Researcher at National Institutes of Health
Publications - 72
Citations - 2355
Sara Ferrando-Martinez is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Immune system & Maraviroc. The author has an hindex of 26, co-authored 63 publications receiving 2002 citations. Previous affiliations of Sara Ferrando-Martinez include Complutense University of Madrid & Spanish National Research Council.
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Journal ArticleDOI
Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals
Jorge F. Vázquez-Castellanos,Sergio Serrano-Villar,Amparo Latorre,Alejandro Artacho,María Loreto Ferrús,Nadia Madrid,A. Vallejo,Talia Sainz,Javier Martínez-Botas,Sara Ferrando-Martinez,Mar Vera,Fernando Dronda,Manuel Leal,J del Romero,Santiago Moreno,Vicente Estrada,María José Gosalbes,Andrés Moya +17 more
TL;DR: Systemic markers of innate and adaptive immunity in a cohort of HIV-infected individuals on successful antiretroviral therapy without comorbidities and in healthy non-HIV- infected subjects are determined.
Journal ArticleDOI
CMV and Immunosenescence: from basics to clinics
Rafael Solana,Raquel Tarazona,Allison E. Aiello,Arne N. Akbar,Victor Appay,Mark Beswick,Jos A. Bosch,Jos A. Bosch,Carmen Campos,Sara Cantisán,Luka Cicin-Sain,Evelyna Derhovanessian,Sara Ferrando-Martinez,Daniela Frasca,Tamas Fulop,Sheila Govind,Beatrix Grubeck-Loebenstein,Ann B. Hill,Mikko Hurme,Florian Kern,Anis Larbi,Miguel López-Botet,Andrea B. Maier,Janet E. McElhaney,Paul Moss,Elissaveta Naumova,Janko Nikolich-Zugich,Alejandra Pera,Jerrald L. Rector,Natalie E. Riddell,Beatriz Sanchez-Correa,Paolo Sansoni,Delphine Sauce,René A. W. van Lier,George C. Wang,Mark R. Wills,Maciej Zieliński,Graham Pawelec +37 more
TL;DR: Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization ofCMV-specific T cells, impact of CMVs infection and ageing on innate immunity, and finally, most important, the clinical implications of immun Rosenescence and CMV infection.
Journal ArticleDOI
Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies.
Constantinos Petrovas,Sara Ferrando-Martinez,Michael Y. Gerner,Joseph P. Casazza,Amarendra Pegu,Claire Deleage,Arik Cooper,Jason Hataye,Sarah Andrews,David R. Ambrozak,Perla M. Del Rio Estrada,Eli Boritz,Robert Paris,Eirini Moysi,Kristin L. Boswell,Ezequiel Ruiz-Mateos,Ilias Vagios,Manuel Leal,Yuria Ablanedo-Terrazas,Amaranta Rivero,Luz A. González-Hernández,Adrian B. McDermott,Susan Moir,Gustavo Reyes-Terán,Fernando Docobo,Giuseppe Pantaleo,Daniel C. Douek,Michael R. Betts,Jacob D. Estes,Ronald N. Germain,John R. Mascola,Richard A. Koup +31 more
TL;DR: The results indicate that CD8 T cells with potent cytolytic activity are recruited to GCs during HIV infection and, if appropriately redirected to kill HIV-infected cells, could be an effective component of an HIV cure strategy.
Journal ArticleDOI
New advances in CMV and immunosenescence.
Paolo Sansoni,Rosanna Vescovini,Francesco Fagnoni,Arne N. Akbar,Ramon Arens,Yen-Ling Chiu,Luka Cicin-Sain,Julie Déchanet-Merville,Evelyna Derhovanessian,Sara Ferrando-Martinez,Claudio Franceschi,Daniela Frasca,Tamas Fulop,David Furman,Effrossyni Gkrania-Klotsas,Felicia Goodrum,Beatrix Grubeck-Loebenstein,Mikko Hurme,Florian Kern,Daniele Lilleri,Miguel López-Botet,Andrea B. Maier,Thomas F. Marandu,Arnaud Marchant,Catharina Matheï,Paul Moss,Aura Muntasell,Ester B. M. Remmerswaal,Natalie E. Riddell,Kathrin Rothe,Delphine Sauce,Eui-Cheol Shin,Amanda M. Simanek,Megan J. Smithey,Cecilia Söderberg-Nauclér,Rafael Solana,Paul G. Thomas,René A. W. van Lier,Graham Pawelec,Janko Nikolich-Zugich +39 more
TL;DR: The attendees of the 4th International Workshop on "CMV & Immunosenescence", held in Parma, Italy, 25-27th March, 2013, presented and discussed data related to these open questions, which are reported in this commentary.
Journal ArticleDOI
Age-related deregulation of naive T cell homeostasis in elderly humans
Sara Ferrando-Martinez,Ezequiel Ruiz-Mateos,Ana Hernández,E Gutierrez,Maria del Mar Rodríguez-Méndez,Antonio Ordóñez,Manuel Leal +6 more
TL;DR: A homeostatic deregulation, affecting mostly the naive CD8 T cell subset, leading to the accumulation of age-associated defects in, otherwise, phenotypically naive T cells is suggested.