J
Jose A. Gavira
Researcher at Spanish National Research Council
Publications - 129
Citations - 3421
Jose A. Gavira is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Crystallization & Protein crystallization. The author has an hindex of 28, co-authored 112 publications receiving 2841 citations. Previous affiliations of Jose A. Gavira include Tohoku University & University of Alabama in Huntsville.
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Journal ArticleDOI
Enhanced Stability against Radiation Damage of Lysozyme Crystals Grown in Fmoc-CF Hydrogels
Rafael Contreras-Montoya,Albert Castellví,Guillermo Escolano-Casado,Judith Juanhuix,Mayte Conejero-Muriel,Modesto T. López-López,Juan M. Cuerva,Luis Álvarez de Cienfuegos,Jose A. Gavira +8 more
TL;DR: In this paper, Fmoc-CF (Cys-Phe) hydrogels, unlike those grown in agarose, give rise to composite crystals that have an enhanced resistance against degradation caused by an intense expo...
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Production of cross-linked lipase crystals at a preparative scale
Raquel Fernández-Penas,Cristóbal Verdugo-Escamilla,Sergio Martínez-Rodríguez,Sergio Martínez-Rodríguez,Jose A. Gavira +4 more
TL;DR: This work presents the crystallization and preparative-scale production of reinforced cross-linked lipase crystals (RCLLCs) using a commercial detergent additive as a raw material and determined the three-dimensional (3D) models of this commercial lipase crystallized with and without phosphate at 2.0 and 1.7 Å resolutions.
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The structural basis for signal promiscuity in a bacterial chemoreceptor.
TL;DR: High‐resolution structures of PcaY_PP‐LBD in the absence and presence of four cognate chemoeffectors and glycerol indicate a significant amount of structural and functional diversity among 4HB domains, and comparisons with the Tar and Tsr chemoreceptors revealed significant structural differences.
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On the Quality of Protein Crystals Grown under Diffusion Mass-transport Controlled Regime (I)
Jose A. Gavira,Fermín Otálora,L. A. González-Ramírez,Emilio Melero,Alexander E. S. Van Driessche,Juan Manuel García-Ruiz +5 more
TL;DR: In this paper, the authors compared the crystal quality of two model (thaumatin and insulin) and two target (HBII and HBII-III) proteins grown by two different methods to reduce/eliminate convective mass transport.
Journal ArticleDOI
Histamine: A Bacterial Signal Molecule.
Tino Krell,Jose A. Gavira,Félix Velando,Matilde Fernández,Amalia Roca,Elizabet Monteagudo-Cascales,Miguel A. Matilla +6 more
TL;DR: The role of histamine as an inter-domain signaling molecule is an emerging field of research and future investigation is required to assess its potential general nature as discussed by the authors, which may play an important role in interdomain and inter-species communication.