J
José D. Santos
Researcher at University of Porto
Publications - 245
Citations - 6520
José D. Santos is an academic researcher from University of Porto. The author has contributed to research in topics: Bone regeneration & Regeneration (biology). The author has an hindex of 45, co-authored 220 publications receiving 5875 citations. Previous affiliations of José D. Santos include Technical University of Lisbon & Faculdade de Engenharia da Universidade do Porto.
Papers
More filters
Journal ArticleDOI
Structural analysis of Si-substituted hydroxyapatite: zeta potential and X-ray photoelectron spectroscopy.
TL;DR: XPS results indicated that silicon seems to be preferentially leached out from Si–HA surface compared to other ionic species after dissolution studies in tris-buffer using a dynamic system.
Journal ArticleDOI
Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applications.
Tiago Valente,Dina M. Silva,Pedro S. Gomes,Maria Helena Fernandes,José D. Santos,Vitor Sencadas +5 more
TL;DR: In vitro results indicate that both UV and γ-radiation treatments of PLA membranes allow the adhesion and proliferation of MG 63 osteoblastic cells in a close interaction with the fiber meshes and with a growth pattern highly sensitive to the underlying random or aligned fiber orientation.
Journal ArticleDOI
In vitro cytocompatibility of MG63 cells on chitosan-organosiloxane hybrid membranes.
Yuki Shirosaki,Kanji Tsuru,Satoshi Hayakawa,Akiyoshi Osaka,Maria A. Lopes,José D. Santos,Maria Helena Fernandes +6 more
TL;DR: CaCl2 was introduced in chitosan-silicate hybrids in expectation that it would improve cell adhesion and differentiation of the hybrid surfaces, but this did not improve cell attachment and proliferation on their surfaces.
Journal ArticleDOI
Ultrastructural comparison of dissolution and apatite precipitation on hydroxyapatite and silicon-substituted hydroxyapatite in vitro and in vivo.
Alexandra E. Porter,Cláudia Botelho,Maria A. Lopes,José D. Santos,Serena M. Best,William Bonfield +5 more
TL;DR: It is suggested that proteins in the in vivo milieu modify the processes of dissolution from the implant, which predominates at the crystallite surfaces in SBF, whereas grain boundary dissolution predominates in vivo.
Journal ArticleDOI
Human osteoblast response to silicon-substituted hydroxyapatite.
Cláudia Botelho,Roger A. Brooks,Serena M. Best,Maria A. Lopes,José D. Santos,Neil Rushton,William Bonfield +6 more
TL;DR: The results indicate that human osteoblasts are affected by the presence of silicon in the HA substrate and that the timing of these effects may be dependent upon the level of silicon substitution.