J
Jose-Felipe Golib-Dzib
Researcher at Janssen-Cilag
Publications - 3
Citations - 181
Jose-Felipe Golib-Dzib is an academic researcher from Janssen-Cilag. The author has contributed to research in topics: Chemogenomics & Deep learning. The author has an hindex of 3, co-authored 3 publications receiving 105 citations.
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ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics
Jiangming Sun,Nina Jeliazkova,Vladimir Chupakhin,Jose-Felipe Golib-Dzib,Ola Engkvist,Lars Carlsson,Jörg K. Wegner,Hugo Ceulemans,Ivan Georgiev,Vedrin Jeliazkov,Nikolay Kochev,Thomas J. Ashby,Hongming Chen +12 more
TL;DR: In this article, the authors compile a comprehensive chemogenomics dataset with over 70 million SAR data points from publicly available databases (PubChem and ChEMBL) including structure, target information and activity annotations.
Journal ArticleDOI
Industry-scale application and evaluation of deep learning for drug target prediction
Noé Sturm,Andreas Mayr,Thanh Le Van,Vladimir Chupakhin,Hugo Ceulemans,Joerg Wegner,Jose-Felipe Golib-Dzib,Nina Jeliazkova,Yves Vandriessche,Stanislav Böhm,Vojtech Cima,Jan Martinovič,Nigel Greene,Tom Vander Aa,Thomas J. Ashby,Sepp Hochreiter,Ola Engkvist,Günter Klambauer,Hongming Chen +18 more
TL;DR: This is the first large-scale study evaluating the potential of machine learning and especially deep learning directly at the level of industry-scale settings and moreover investigating the transferability of publicly learned target prediction models towards industrial bioactivity prediction pipelines.
Journal ArticleDOI
Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics
Jiangming Sun,Nina Jeliazkova,Vladimir Chupakhin,Jose-Felipe Golib-Dzib,Ola Engkvist,Lars Carlsson,Jörg K. Wegner,Hugo Ceulemans,Ivan Georgiev,Vedrin Jeliazkov,Nikolay Kochev,Thomas J. Ashby,Hongming Chen +12 more
TL;DR: The aspiration is to create a useful chemogenomics resource reflecting industry‐scale data not only for building predictive models of in silico polypharmacology and off‐ target effects but also for the validation of cheminformatics approaches in general.