J
Jose Luis Parra
Researcher at Spanish National Research Council
Publications - 69
Citations - 2116
Jose Luis Parra is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Liposome & Pulmonary surfactant. The author has an hindex of 22, co-authored 69 publications receiving 1952 citations.
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Ceramides and skin function.
TL;DR: The link between skin disorders and changes in barrier lipid composition, especially in ceramides, is difficult to prove, however, most skin disorders that have a diminished barrier function present a decrease in total ceramide content with some differences in the ceramide pattern.
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Enzymatic acylation of di- and trisaccharides with fatty acids: choosing the appropriate enzyme, support and solvent
Francisco J. Plou,M. Angeles Cruces,Manuel Ferrer,Gloria Fuentes,Eitel Pastor,Manuel Bernabé,Morten Würtz Christensen,Francisco Comelles,Jose Luis Parra,Antonio Ballesteros +9 more
TL;DR: The use of mixtures of miscible solvents (e.g. dimethylsulfoxide and 2-methyl-2-butanol) as a general strategy to acylate enzymatically hydrophilic substrates is proposed and it is observed that decreasing the hydrophobicity of the medium can be substantially enhanced.
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Direct formation of mixed micelles in the solubilization of phospholipid liposomes by Triton X-100.
Olga López,Alfonso de la Maza,Luisa Coderch,Carmen López-Iglesias,Ernst Wehrli,Jose Luis Parra +5 more
TL;DR: Vesicle to micelle transformation was mainly governed by the progressive formation of mixed micelles within the bilayer, which led to a complete solubilization of liposomes.
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Comparative surface activities of di- and trisaccharide fatty acid esters
Manuel Ferrer,Francisco Comelles,Francisco J. Plou,M. Angeles Cruces,Gloria Fuentes,Jose Luis Parra,Antonio Ballesteros +6 more
TL;DR: In this article, enzymes were used to synthesize di-and trisaccharide-based surfactants with critical micelle concentration (CMC) values in the range 2−250 µm with surface tension values ranging from 24.5 to 36.5 µm.
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Surface-Active Properties of Lipophilic Antioxidants Tyrosol and Hydroxytyrosol Fatty Acid Esters: A Potential Explanation for the Nonlinear Hypothesis of the Antioxidant Activity in Oil-in-Water Emulsions
Ricardo Lucas,Francisco Comelles,David Alcantara,Olivia S. Maldonado,Melanie Curcuroze,Jose Luis Parra,Juan C. Morales +6 more
TL;DR: It is found that tyrosol and hydroxytyrosol fatty acid esters are relevant surfactants when the right hydrophilic-lipophilic balance (HLB) is attained and, in some cases, as efficient as emulsifiers commonly used in industry, such as Brij 30 or Tween 20.