J
José María Carazo
Researcher at Spanish National Research Council
Publications - 318
Citations - 14572
José María Carazo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Image processing & Iterative reconstruction. The author has an hindex of 59, co-authored 309 publications receiving 12499 citations. Previous affiliations of José María Carazo include University of Málaga & University of Almería.
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Challenges ahead Electron Microscopy for Structural Biology from the Image Processing point of view.
TL;DR: Here the focus is on image processing aspects, particularly in the so-called area of Single Particle Analysis, discussing some of the current resolution and high-throughput limiting factors.
Journal ArticleDOI
A framework for querying a database for structural information on 3D images of macromolecules: A web-based query-by-content prototype on the BioImage macromolecular server.
TL;DR: This work focuses on the development of new mechanisms aimed at "querying" these databases of complex data sets by their intrinsic content, rather than by their textual annotations only, and implements a first prototype of a "query-by-content" system.
Journal ArticleDOI
New phylogenetic venues opened by a novel implementation of the DNAml algorithm
TL;DR: The parallelization of a key biological application, such as the construction of phylogenetic trees, using the DNAml program is described, using an efficient parallelization that scaled very well to large problem sizes.
Journal ArticleDOI
Detection, classification and 3D reconstruction of biological macromolecules on hypercube computers.
TL;DR: It is shown how the rich topology of the hypercube, combined with an efficient programming strategy, allows for order-of-magnitude increase in computational capacity for such time-consuming tasks as calculation of multidimensional FFT's, cross-correlation coefficients, fuzzy partitioning functionals and the filtered back-projection 3D reconstruction method.
Book ChapterDOI
Fully Three-Dimensional Reconstruction in Electron Microscopy
TL;DR: The conclusion is that ART with blobs produces high quality reconstructions and is, in particular, superior to WBP in recovering features along the “vertical” direction.