C
Carlos Oscar S. Sorzano
Researcher at Spanish National Research Council
Publications - 233
Citations - 9273
Carlos Oscar S. Sorzano is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Antigen & Virus. The author has an hindex of 41, co-authored 221 publications receiving 7281 citations. Previous affiliations of Carlos Oscar S. Sorzano include Tel Aviv University & Autonomous University of Madrid.
Papers
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Journal ArticleDOI
XMIPP: a new generation of an open-source image processing package for electron microscopy
Carlos Oscar S. Sorzano,Roberto Marabini,Javier Velázquez-Muriel,J.R. Bilbao-Castro,Sjors H.W. Scheres,José María Carazo,Alberto Pascual-Montano +6 more
TL;DR: A general overview of a new generation of Xmipp that has been re-engineered to maximize flexibility and modularity, potentially facilitating its integration in future standardization efforts in the field.
Journal ArticleDOI
Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy.
J.M. de la Rosa-Trevín,A. Quintana,L. del Cano,A. Zaldívar,I. Foche,J. Gutiérrez,Josué Gómez-Blanco,Jordi Burguet-Castell,J. Cuenca-Alba,Vahid Abrishami,Javier Vargas,Joaquín Otón,Grigory Sharov,José Luis Vilas,J. Navas,P. Conesa,Mohsen Kazemi,Roberto Marabini,Carlos Oscar S. Sorzano,Carlos Oscar S. Sorzano,José María Carazo +20 more
TL;DR: Scipion is a software framework for integrating several 3DEM software packages through a workflow-based approach that allows the execution of reusable, standardized, traceable and reproducible image-processing protocols.
Journal ArticleDOI
DeepEMhancer: a deep learning solution for cryo-EM volume post-processing.
Rubén J. Sánchez-García,Rubén J. Sánchez-García,Josué Gómez-Blanco,Josué Gómez-Blanco,Ana Maria Cuervo,José María Carazo,Carlos Oscar S. Sorzano,Javier Vargas,Javier Vargas +8 more
TL;DR: DeepEMhancer as mentioned in this paper is a deep learning approach designed to perform automatic post-processing of cryo-EM maps, trained on a dataset of pairs of experimental maps and maps sharpened using their respective atomic models, has learned how to post-process experimental maps performing masking-like and sharpening-like operations.
Journal ArticleDOI
Image processing for electron microscopy single-particle analysis using XMIPP
Sjors H.W. Scheres,Rafael Núñez-Ramírez,Carlos Oscar S. Sorzano,José María Carazo,Roberto Marabini +4 more
TL;DR: A collection of standardized image processing protocols for electron microscopy single-particle analysis using the XMIPP software package that allows performing the entire processing workflow starting from digitized micrographs up to the final refinement and evaluation of 3D models.
Journal ArticleDOI
Elastic registration of biological images using vector-spline regularization
TL;DR: The method combines and extends some of the best techniques available in the context of medical imaging and expresses the deformation field as a B-spline model, which allows the algorithm to deal with a rich variety of deformations.