J
José Rodrigo
Researcher at Complutense University of Madrid
Publications - 127
Citations - 5412
José Rodrigo is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Nitric oxide synthase & Nitric oxide. The author has an hindex of 37, co-authored 124 publications receiving 5266 citations. Previous affiliations of José Rodrigo include Spanish National Research Council & Technical University of Madrid.
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Journal ArticleDOI
Localization of Nitric Oxide Synthase in the Adult Rat Brain
José Rodrigo,David R. Springall,O. Uttenthal,M. L. Bentura,Francisco Abadía-Molina,Valentina Riveros-Moreno,Ricardo Martínez-Murillo,Julia M. Polak,Salvador Moncada +8 more
TL;DR: The distribution of the immunoreactivity to nitric oxide synthase has been examined from rostral to caudal areas of the rat central nervous system using light microscopy.
Journal ArticleDOI
Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain.
José L. M. Madrigal,Raquel Olivenza,María A. Moro,Ignacio Lizasoain,Pedro Lorenzo,José Rodrigo,Juan C. Leza +6 more
TL;DR: The results suggest that a sustained overproduction of NO via iNOS is responsible, at least in part, of the inhibition of mitochondrial respiratory chain caused by stress and that this pathway also accounts for the oxidative stress found in this situation.
Journal ArticleDOI
Presence of nitric oxide synthase activity in roots and nodules of Lupinus albus.
Mercedes Cueto,Octavio Hernández-Perera,Raquel Martín,M. L. Bentura,José Rodrigo,Santiago Lamas,Maria Pilar Golvano +6 more
TL;DR: Results indicate the presence of a putative nitric oxide synthase in plants, which was synthesized by roots and nodules of Lupinus albus in an l‐arginine‐dependent manner.
Journal ArticleDOI
Expression of Constitutive and Inducible Nitric Oxide Synthases in the Vascular Wall of Young and Aging Rats
María R. Cernadas,Lourdes Sánchez de Miguel,Margarita García-Durán,F. González-Fernández,I. Millás,M Montón,José Rodrigo,Luis Rico,Patricia Fernandez,Trinidad de Frutos,Juan A. Rodríguez-Feo,Jose Luis Lopez Guerra,Carlos Caramelo,S. Casado,Antonio López-Farré +14 more
TL;DR: An impaired hypotensive response to acetylcholine and bradykinin (2 NO- and endothelium-dependent hypotensive agents) that was accompanied by a preserved hypotensive responded to sodium nitroprusside was found in aging rats, which could explain the impaired endothelia-dependenthypotensive response associated with aging.
Journal ArticleDOI
Occurrence, distribution and ontogeny of CGRP immunoreactivity in the rat lower respiratory tract: effect of capsaicin treatment and surgical denervations.
A Cadieux,David R. Springall,P.K. Mulderry,José Rodrigo,M. A. Ghatei,G. Terenghi,S.R. Bloom,J.M. Polak +7 more
TL;DR: It is concluded that CGRP immunoreactivity is localized in both nerve fibres and endocrine cells and is associated principally with the afferent (sensory) innervation of the respiratory tract.