J
José Such
Researcher at Carlos III Health Institute
Publications - 20
Citations - 3417
José Such is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Cirrhosis & Spontaneous bacterial peritonitis. The author has an hindex of 17, co-authored 20 publications receiving 3141 citations. Previous affiliations of José Such include Universidad Miguel Hernández de Elche & University of Barcelona.
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Journal ArticleDOI
Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013
Rajiv Jalan,Javier Fernández,Reiner Wiest,Bernd Schnabl,Richard Moreau,Paolo Angeli,Vanessa Stadlbauer,Thierry Gustot,Mauro Bernardi,Rafael Cantón,Agustín Albillos,Frank Lammert,Alexander Wilmer,Rajeshwar P. Mookerjee,Jordi Vila,R. Garcia-Martinez,Julia Wendon,José Such,Juan Córdoba,Arun J. Sanyal,Guadalupe Garcia-Tsao,Vicente Arroyo,Andrew K. Burroughs,Pere Ginès +23 more
TL;DR: An in-depth review and a position statement on bacterial infections in cirrhosis are reported, which suggest that research on biomarkers of early infection may be useful in early diagnosis and treatment of infections.
Journal ArticleDOI
Primary Prophylaxis of Spontaneous Bacterial Peritonitis Delays Hepatorenal Syndrome and Improves Survival in Cirrhosis
Javier Fernández,Miquel Navasa,Ramon Planas,Silvia Montoliu,David Monfort,Germán Soriano,Carmen Vila,Alberto Pardo,Enrique Quintero,Victor Vargas,José Such,Pere Ginès,Vicente Arroyo +12 more
TL;DR: In this paper, the authors showed that primary prophylaxis with norfloxacin has a great impact in the clinical course of patients with advanced cirrhosis, reducing the incidence of spontaneous bacterial peritonitis, delaying the development of hepatorenal syndrome, and improving survival.
Journal ArticleDOI
Detection and identification of bacterial DNA in patients with cirrhosis and culture-negative, nonneutrocytic ascites☆
José Such,Rubén Francés,Carlos Muñoz,Pedro Zapater,Juan Antonio Casellas,Ana Cifuentes,Francisco Rodriguez-Valera,Sonia Pascual,Javier Sola-Vera,F. Carnicer,Francisco Uceda,José María Palazón,Miguel Pérez-Mateo +12 more
TL;DR: In this article, the authors investigated the hypothetical presence of bacteria in blood and/or ascitic fluid (AF) from patients with cirrhosis and sterile (culture negative) AF by means of bacterial DNA (bactDNA) detection and identification.
Journal ArticleDOI
Randomized trial comparing albumin and saline in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites.
Javier Sola-Vera,Josep Miñana,Elena Ricart,Montserrat Planella,Begoña González,Xavier Torras,J. Rodriguez,José Such,Sonia Pascual,Germán Soriano,Miguel Pérez-Mateo,Carlos Guarner +11 more
TL;DR: In conclusion, albumin is more effective than saline in the prevention of PICD and is a valid alternative to albumin when less than 6 L of ascitic fluid is evacuated.
Journal ArticleDOI
Addition of Simvastatin to Standard Therapy for the Prevention of Variceal Rebleeding Does Not Reduce Rebleeding but Increases Survival in Patients With Cirrhosis
Juan G. Abraldes,Càndid Villanueva,Carles Aracil,Juan Turnes,Manuel Hernández-Guerra,Joan Genescà,Manuel J. Rodriguez,José Castellote,Juan Carlos García-Pagán,Ferran Torres,Jose Luis Calleja,Agustín Albillos,Jaime Bosch,Salvador Augustin,Elba Llop,Dalia Morales Arraez,Goretti Hernández Mesa,Javier Martínez,Enric Reverter,Susana Seijo,Fanny Turon,Josep Miñana,Juan Buenestado,Josep Maria Reñe,Carmen A. Navacués,Ramon Planas,Rosa Maria Morillas,Pau Bellot,José Such,Mercedes Vergara,Angela Puente,Joaquín de la Peña,José Mera Calviño,Laura Rivas Moral,Oana Pavel,Edilmar Alvarado,Alba Ardevol,A. Girbau,Alba Cachero,Joan Albert Arnaiz,Annalisa Berzigotti,Judit Pich,José Ríos,Rosa Saenz,Laura Millán,Helena Beleta,Núria Ramos +46 more
TL;DR: In a randomized controlled trial, addition of simvastatin to standard therapy did not reduce rebleeding, but was associated with a survival benefit for patients with Child-Pugh class A or B cirrhosis.