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Joseph A. Caruso

Researcher at Wayne State University

Publications -  463
Citations -  15645

Joseph A. Caruso is an academic researcher from Wayne State University. The author has contributed to research in topics: Inductively coupled plasma mass spectrometry & Mass spectrometry. The author has an hindex of 61, co-authored 462 publications receiving 14811 citations. Previous affiliations of Joseph A. Caruso include University of Texas MD Anderson Cancer Center & University of North Carolina at Chapel Hill.

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Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage.

TL;DR: It is demonstrated that photodamaged lysosomes trigger the mitochondrial apoptotic pathway by releasing proteases that activate Bid, including pro-caspase-3 activation.
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Overexpression of Selenocysteine Methyltransferase in Arabidopsis and Indian Mustard Increases Selenium Tolerance and Accumulation

TL;DR: This is the first study, to the authors' knowledge, in which a fast-growing plant was genetically engineered to overexpress a gene from a hyperaccumulator in order to increase phytoremediation potential.
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Arsenic and its speciation analysis using high-performance liquid chromatography and inductively coupled plasma mass spectrometry.

TL;DR: This review describes the essential background and toxicity of arsenic in the environment, and more importantly, some currently used chromatographic applications and sample handling procedures necessary to accurately detect and quantify arsenic in its various chemical forms.
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Liquid chromatography–inductively coupled plasma mass spectrometry

TL;DR: This review focuses on the basic principles of LC-ICP-MS, its historical development and the many ways in which this technique can be applied.
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Granulocyte Macrophage-Colony Stimulating Factor Induced Zn Sequestration Enhances Macrophage Superoxide and Limits Intracellular Pathogen Survival

TL;DR: It is found that GM-CSF-activated infected macrophages sequestered labile Zn by inducing binding to metallothioneins (MTs) in a STAT3 and STAT5 transcription-factor-dependent manner, illuminating a GM- CSF-induced Zn-sequestration network that drives phagocyte antimicrobial effector function.