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Joseph H. Rapp

Researcher at University of California, San Francisco

Publications -  139
Citations -  11394

Joseph H. Rapp is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Chylomicron & Cholesterol. The author has an hindex of 58, co-authored 137 publications receiving 10909 citations. Previous affiliations of Joseph H. Rapp include United States Department of Veterans Affairs & Oregon Health & Science University.

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Journal ArticleDOI

Composition and metabolism of symptomatic distal aortic plaque.

TL;DR: The most striking feature of advanced human atherosclerotic lesions removed by endarterectomy is an enormous accumulation of calcium that was raised more than tenfold, from a level of about 3% of dry tissue weight in the normal tissue to values approaching 50% in the pathologic specimens.
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Chylomicron and Chylomicron Remnant Metabolism in STZ-Induced Diabetic Rats

TL;DR: With affinity chromatography, it was found that the increase in serum triglycerides levels in diabetic rats was due to triglyceride-rich very-low-density lipoproteins and/or CM and not to the accumulation of remnants, which supports the observation that remnant clearance is not impaired.
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Testosterone regulates metabolism of plasma chylomicrons in rats.

TL;DR: The results indicate that the differences in chylomicron metabolism, postheparin lipoprotein lipase activities, and serum high density lipop protein levels observed between male and female rats are due to testosterone.
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Apolipoprotein E4 Domain Interaction Accelerates Diet-Induced Atherosclerosis in Hypomorphic Arg-61 Apoe Mice

TL;DR: Data indicate that domain interaction mediates proatherogenic effects of apoE4 in part by modulating lipoprotein metabolism and macrophage biology and Pharmaceutical targeting of domain interaction could lead to new treatments for atherosclerosis in apo E4 individuals.