J
Joseph P. M. Hui
Researcher at Halifax
Publications - 27
Citations - 1031
Joseph P. M. Hui is an academic researcher from Halifax. The author has contributed to research in topics: Medicine & Campylobacter jejuni. The author has an hindex of 15, co-authored 22 publications receiving 940 citations. Previous affiliations of Joseph P. M. Hui include National Research Council.
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Journal ArticleDOI
Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens.
Sarah L. Howard,Aparna Jagannathan,Evelyn C. Soo,Joseph P. M. Hui,Annie Aubry,Imran Ahmed,Andrey V. Karlyshev,John F. Kelly,Michael Jones,Mark P. Stevens,Susan M. Logan,Brendan W. Wren +11 more
TL;DR: In this article, the authors report mutagenesis, functional, and structural data to confirm that this locus, and Cj1324 in particular, has a significant contributory role in the colonization of chickens by C. jejuni.
Journal ArticleDOI
Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach
David J. McNally,Joseph P. M. Hui,Annie Aubry,Kenneth K.K. Mui,Patricia Guerry,Jean-Robert Brisson,Susan M. Logan,Evelyn C. Soo +7 more
TL;DR: A focused metabolomics approach to define the function of flagellin glycosylation genes in Campylobacter jejuni and demonstrate the usefulness of this approach for targeting compounds within the bacterial metabolome to assign function to genes, identify metabolic intermediates, and elucidate novel biosynthetic pathways.
Journal ArticleDOI
Targeted Metabolomics Analysis of Campylobacter coli VC167 Reveals Legionaminic Acid Derivatives as Novel Flagellar Glycans
David J. McNally,Annie Aubry,Joseph P. M. Hui,Nam Huan Khieu,Dennis M. Whitfield,Cheryl P. Ewing,Patricia Guerry,Jean-Robert Brisson,Susan M. Logan,Evelyn C. Soo +9 more
TL;DR: It is demonstrated that, in addition to CMP-pseudaminic acid, C. coli VC167 also produces two structurally distinct nucleotide-activated nonulosonate sugars that were observed as negative ions at m/z 637 and m/Z 651 (CMP-315 and CMP -329).
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Rapid determination of corticosteroids in urine by combined solid phase microextraction/liquid chromatography/mass spectrometry
TL;DR: A comparison of the SPME/LC/MS method with LC/MS methods utilizing traditional sample preparation techniques, shows that the former offers similar performance in terms of precision, linearity and detection limits, but is clearly easier to use and faster to perform.
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Screening for multiple classes of marine biotoxins by liquid chromatography-high-resolution mass spectrometry.
TL;DR: The use of a benchtop Orbitrap system for liquid chromatography–mass spectrometry (LC-MS) screening of multiple classes of biotoxins commonly found in shellfish yielded mass accuracy of less than 1 ppm error at a resolving power of 100,000 for the analytes studied.