M
Michael Jones
Researcher at University of Nottingham
Publications - 76
Citations - 5388
Michael Jones is an academic researcher from University of Nottingham. The author has contributed to research in topics: Campylobacter jejuni & Salmonella. The author has an hindex of 35, co-authored 76 publications receiving 4792 citations. Previous affiliations of Michael Jones include Newbury College & University of Leicester.
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Journal ArticleDOI
Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity.
TL;DR: The characterization of a new gene family required for MscS function, YggB and KefA, is reported, which has enabled a rigorous test of the role of the channels.
Journal ArticleDOI
Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways.
Nicholas R. Thomson,Debra J. Clayton,Daniel Windhorst,Georgios S. Vernikos,Susanne Davidson,Carol Churcher,Michael A. Quail,Mark P. Stevens,Michael Jones,Michael Watson,Andy Barron,Abigail N. Layton,Derek Pickard,Robert A. Kingsley,Alex Bignell,Louise Clark,Barbara Harris,Doug Ormond,Zahra Abdellah,Karen Brooks,Inna Cherevach,Tracey Chillingworth,John Woodward,Halina Norberczak,Angela Lord,Claire Arrowsmith,Kay Jagels,Sharon Moule,Karen Mungall,Mandy Sanders,Sally Whitehead,José A. Chabalgoity,Duncan J. Maskell,Tom J. Humphrey,Mark Roberts,Paul A. Barrow,Gordon Dougan,Julian Parkhill +37 more
TL;DR: Genome comparisons between these and other Salmonella isolates indicate that S. Gallinarum 287/91 is a recently evolved descendent of S. Enteritidis, and it is proposed that experimental analysis in chickens and mice could provide an experimentally tractable route toward unraveling the genetic basis of host adaptation in S. enterica.
Journal ArticleDOI
Identification of a pathogenicity island required for Salmonella enteropathogenicity.
Michael W. Wood,Michael Jones,Patricia R. Watson,Samantha Hedges,Tim S. Wallis,Edouard E. Galyov +5 more
TL;DR: It is shown that sopB is located on a large DNA fragment unique to the Salmonella chromosome, which has features characteristic of ‘pathogenicity islands’ and, therefore, it was denoted SPI‐5 (Salmonella pathogenicity island‐5).
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The immunobiology of avian systemic salmonellosis.
TL;DR: Preliminary evidence of modulation of adaptive immunity away from a Th1 response to facilitate the development of the carrier state is shown.
Journal ArticleDOI
Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract.
Michael Jones,Kerrie L. Marston,Claire A. Woodall,Duncan J. Maskell,Dennis Linton,Andrey V. Karlyshev,Nick Dorrell,Brendan W. Wren,Paul A. Barrow +8 more
TL;DR: This study showed that there was colonization of the avian intestinal tract by a Campylobacter strain having a known genome sequence, and it provides a model for colonization and persistence studies with specific mutations.