Joseph R. Nevins

TL;DR: It is concluded that activation of E2F, as a posttranslational event, is responsible for the stimulation of E 2 transcription by E1A.

TL;DR: Among a cohort of patients with NSCLC, subgroups defined by oncogenic pathway activation profiles were associated with recurrence-free survival, and these findings require validation in independent patient data sets.

TL;DR: It is suggested that the cohort of patients with coactivation of TTF-1 and NKX2–8 pathways appears to be resistant to standard cisplatin therapy, suggesting the need for alternative therapies in this cohort of high-risk patients.

TL;DR: It is found that there is a substantial decrease in the level of CF1 activity when an adenovirus infection proceeds to the late phase, and it is suggested that this reduction inCF1 activity contributes to the reduced use of the L1 poly(A) site during the late stage of anAdenov virus infection.

TL;DR: The ability to predict APS, but more importantly, those patients at risk for venous thrombosis, represents a paradigm for a genomic approach that can be applied to other populations of patients with venousThromBosis, providing for more effective clinical management of disease, while also reflecting the possible underlying biologic processes.