J
Josh Dubnau
Researcher at Stony Brook University
Publications - 57
Citations - 4195
Josh Dubnau is an academic researcher from Stony Brook University. The author has contributed to research in topics: Endogenous retrovirus & Mushroom bodies. The author has an hindex of 24, co-authored 54 publications receiving 3589 citations. Previous affiliations of Josh Dubnau include State University of New York System & Public Health Research Institute.
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Journal ArticleDOI
The staufen/pumilio Pathway Is Involved in Drosophila Long-Term Memory
Josh Dubnau,Ann-Shyn Chiang,Ann-Shyn Chiang,Lori Grady,Jody Barditch,Scott Gossweiler,John D. McNeil,Patrick Smith,Francois Buldoc,Rod J. Scott,Uli Certa,Clemens Broger,Tim Tully +12 more
TL;DR: Convergent findings from the behavioral screen for memory mutants and DNA microarray analysis of transcriptional responses during memory formation in normal animals suggest the involvement of the pumilio/staufen pathway in memory.
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Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory
TL;DR: It is shown that synaptic transmission from mushroom body neurons is required during memory retrieval but not during acquisition or storage, and it is proposed that the hebbian processes underlying olfactory associative learning reside in mushroom body dendrites or upstream of the mushroom body and that the resulting alterations in synaptic strength modulate mushroom body output during memory retrieved.
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Gene discovery in Drosophila: new insights for learning and memory
Josh Dubnau,Tim Tully +1 more
TL;DR: The current state of genetic analysis of learning and memory in the fruitfly, Drosophila melanogaster, is reviewed, suggesting that core cellular mechanisms of simple forms of learning are evolutionarily conserved and biological pathways discovered in invertebrates are likely to be conserved in vertebrates as well.
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RNA recognition and translational regulation by a homeodomain protein
Josh Dubnau,Gary Struhl +1 more
TL;DR: Evidence is presented that bed also binds RNA and acts as a translational represser to generate an opposing gradient of the homeodomain protein caudal (cad) in Drosophila.
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Deconstructing memory in Drosophila
TL;DR: This essay has tried to discuss particular findings that provide some level of intellectual synthesis across three levels of biological organization: behavior, neural circuitry and biochemical pathways in Drosophila.