J
Joshua S Hersheson
Researcher at Newcastle University
Publications - 1
Citations - 1362
Joshua S Hersheson is an academic researcher from Newcastle University. The author has contributed to research in topics: Mitochondrial DNA & Substantia nigra. The author has an hindex of 1, co-authored 1 publications receiving 1267 citations.
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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender,Kim J. Krishnan,Christopher Morris,Geoffrey A. Taylor,Amy K. Reeve,Robert H. Perry,Evelyn Jaros,Joshua S Hersheson,Joanne Betts,Thomas Klopstock,Robert W. Taylor,Douglass M. Turnbull +11 more
TL;DR: It is shown that in substantia nigra neurons from both aged controls and individuals with Parkinson disease, there is a high level of deleted mitochondrial DNA, suggesting that somatic mtDNA deletions are important in the selective neuronal loss observed in brain aging and in Parkinson disease.