E
Evelyn Jaros
Researcher at Newcastle University
Publications - 96
Citations - 9271
Evelyn Jaros is an academic researcher from Newcastle University. The author has contributed to research in topics: Dementia with Lewy bodies & Dementia. The author has an hindex of 47, co-authored 96 publications receiving 8637 citations. Previous affiliations of Evelyn Jaros include Newcastle upon Tyne Hospitals NHS Foundation Trust & Royal Victoria Infirmary.
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Journal ArticleDOI
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender,Kim J. Krishnan,Christopher Morris,Geoffrey A. Taylor,Amy K. Reeve,Robert H. Perry,Evelyn Jaros,Joshua S Hersheson,Joanne Betts,Thomas Klopstock,Robert W. Taylor,Douglass M. Turnbull +11 more
TL;DR: It is shown that in substantia nigra neurons from both aged controls and individuals with Parkinson disease, there is a high level of deleted mitochondrial DNA, suggesting that somatic mtDNA deletions are important in the selective neuronal loss observed in brain aging and in Parkinson disease.
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A harmonized classification system for FTLD-TDP pathology
Ian R. A. Mackenzie,Manuela Neumann,Atik Baborie,Deepak M. Sampathu,Daniel du Plessis,Evelyn Jaros,Robert H. Perry,John Q. Trojanowski,David M. A. Mann,Virginia M.-Y. Lee +9 more
TL;DR: In this article, Sampathu et al. proposed a new classification system for FTLD-TDP pathology, which is a single harmonized system that replaces the two currently in use.
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Prospective validation of consensus criteria for the diagnosis of dementia with Lewy bodies.
Ian G. McKeith,Clive Ballard,Robert H. Perry,Paul G. Ince,John T. O'Brien,David Neill,K. Lowery,Evelyn Jaros,Robert Barber,Peter L. Thompson,Alan C. Swann,Andrew Fairbairn,Elaine K. Perry +12 more
TL;DR: The Consensus criteria for DLB performed as well in this prospective study as those for AD and VaD, with a diagnostic sensitivity substantially higher than that reported by previous retrospective studies.
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Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution.
M.A. Piggott,Elizabeth F. Marshall,N Thomas,S. Lloyd,J.A. Court,Evelyn Jaros,David J. Burn,Mary Johnson,Robert H. Perry,Ian G. McKeith,Clive Ballard,Elaine K. Perry +11 more
TL;DR: Investigation of dopaminergic activities along the rostrocaudal striatal axis from a post-mortem series indicated compensatory increased turnover in Parkinson's disease, which was absent in DLB despite the loss of substantia nigra neurons, dopamine and uptake sites.
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Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis.
Emma J. Burton,Robert Barber,Elizabeta B. Mukaetova-Ladinska,J. Robson,Robert H. Perry,Evelyn Jaros,Raj N. Kalaria,John T. O'Brien +7 more
TL;DR: MTA on MRI had robust discriminatory power for distinguishing Alzheimer's disease from DLB and VCI in pathologically confirmed cases and may have utility as a means for stratifying samples in vivo on the basis of putative differences in pathology.