J
Jozef Mardiak
Researcher at Comenius University in Bratislava
Publications - 121
Citations - 4504
Jozef Mardiak is an academic researcher from Comenius University in Bratislava. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 25, co-authored 104 publications receiving 3926 citations. Previous affiliations of Jozef Mardiak include National Institutes of Health.
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Journal ArticleDOI
Pazopanib in Locally Advanced or Metastatic Renal Cell Carcinoma: Results of a Randomized Phase III Trial
Cora N. Sternberg,Ian D. Davis,Jozef Mardiak,Cezary Szczylik,Eunsik Lee,John Wagstaff,Carlos H. Barrios,Pamela Salman,Oleg Gladkov,Alexander Kavina,J. J. Zarba,Mei Chen,Lauren McCann,Lini Pandite,Debasish F. Roychowdhury,Robert E. Hawkins +15 more
TL;DR: Pazopanib demonstrated significant improvement in PFS and tumor response compared with placebo in treatment-naive and cytokine-pretreated patients with advanced and/or metastatic RCC.
Journal ArticleDOI
A randomised, double-blind phase III study of pazopanib in patients with advanced and/or metastatic renal cell carcinoma: Final overall survival results and safety update
Cora N. Sternberg,Robert E. Hawkins,John Wagstaff,Pamela Salman,Jozef Mardiak,Carlos H. Barrios,J. J. Zarba,Oleg Gladkov,Eunsik Lee,Cezary Szczylik,Lauren McCann,Stephen D. Rubin,Mei Chen,Ian D. Davis +13 more
TL;DR: Although no significant difference in OS was observed in this study, extensive crossover from placebo to pazopanib confounded final OS analysis and post-hoc analyses adjusting for crossover suggest OS benefit with pazobanib treatment for mRCC patients.
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Prevention of irinotecan induced diarrhea by probiotics: A randomized double blind, placebo controlled pilot study.
Michal Mego,Jozef Chovanec,Iveta Vochyanova-Andrezalova,Peter Konkolovsky,Milada Mikulova,Maria Reckova,Vera Miskovska,Branislav Bystricky,Juraj Beniak,Lenka Medvecova,Adela Lagin,Daniela Svetlovska,Stanislav Spanik,Vladimir Zajac,Jozef Mardiak,Lubos Drgona +15 more
TL;DR: Administration of probiotics in patients with colorectal cancer treated with irinotecan-based chemotherapy is safe and could lead to a reduction in the incidence and severity of gastrointestinal toxicity.
Journal ArticleDOI
Delays in diagnosis and treatment of breast cancer: a multinational analysis
Jacek Jassem,Vahit Ozmen,Florin Bacanu,Monika Drobniene,Janis Eglitis,Kuntegowdanahalli C Lakshmaiah,Zsuzsanna Kahán,Jozef Mardiak,Tadeusz Pienkowski,Tatiana Semiglazova,Ljiljana Stamatovic,Constanta Timcheva,Suzana Vasovic,Damir Vrbanec,Piotr Zaborek +14 more
TL;DR: Cancer diagnosis made by an oncologist versus another physician, higher education level, older age, family history of female cancers and having a breast lump as the first cancer sign were associated with shorter system-related delay times.
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Prognostic value of programmed-death-1 receptor (PD-1) and its ligand 1 (PD-L1) in testicular germ cell tumors
Zuzana Cierna,Michal Mego,Viera Miskovska,Katarina Machalekova,Michal Chovanec,Daniela Svetlovska,Katarina Hainova,Katarina Rejlekova,Dusan Macak,Stanislav Spanik,Dalibor Ondrus,Karol Kajo,Jozef Mardiak,Pavel Babal +13 more
TL;DR: It is shown for the first time, the prognostic value of PD-L1 expression in TGCTs is shown and the data imply that the PD-1/PD-L 1 pathway could be a novel therapeutic target inTGCTs.