K
Karol Kajo
Researcher at Slovak Academy of Sciences
Publications - 130
Citations - 2501
Karol Kajo is an academic researcher from Slovak Academy of Sciences. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 23, co-authored 120 publications receiving 1755 citations. Previous affiliations of Karol Kajo include Comenius University in Bratislava & Slovak Medical University.
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Journal ArticleDOI
Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels
TL;DR: The aim of this review is to summarize the current knowledge addressing the antidiabetic effects of dietary flavonoids and their underlying molecular mechanisms on selected pathways: Glucose transporter, hepatic enzymes, tyrosine kinase inhibitor, AMPK, PPAR, and NF-κB.
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Prognostic value of programmed-death-1 receptor (PD-1) and its ligand 1 (PD-L1) in testicular germ cell tumors
Zuzana Cierna,Michal Mego,Viera Miskovska,Katarina Machalekova,Michal Chovanec,Daniela Svetlovska,Katarina Hainova,Katarina Rejlekova,Dusan Macak,Stanislav Spanik,Dalibor Ondrus,Karol Kajo,Jozef Mardiak,Pavel Babal +13 more
TL;DR: It is shown for the first time, the prognostic value of PD-L1 expression in TGCTs is shown and the data imply that the PD-1/PD-L 1 pathway could be a novel therapeutic target inTGCTs.
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Flavonoids against the SARS-CoV-2 induced inflammatory storm.
Alena Liskova,Marek Samec,Lenka Koklesova,Samson Mathews Samuel,Kevin Zhai,Raghad Khalid Al-Ishaq,Mariam Abotaleb,Vladimir Nosal,Karol Kajo,Milad Ashrafizadeh,Ali Zarrabi,Aranka Brockmueller,Mehdi Shakibaei,Peter Sabaka,Ioana Mozos,David Ullrich,Robert Prosecky,Giampiero La Rocca,Martin Caprnda,Dietrich Büsselberg,Luis Rodrigo,Peter Kruzliak,Peter Kubatka +22 more
TL;DR: The potential role of flavonoids in the modulation of signaling pathways that are crucial for COVID-19 disease, particularly those related to inflammation and immunity, was discussed in this paper.
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Systemic immune-inflammation index in germ-cell tumours.
Michal Chovanec,Zuzana Cierna,Viera Miskovska,Katarina Machalekova,Katarina Kalavska,Katarina Kalavska,Katarina Rejlekova,Daniela Svetlovska,Dusan Macak,Stanislav Spanik,Karol Kajo,Pavel Babal,Ugo De Giorgi,Michal Mego,Jozef Mardiak +14 more
TL;DR: Combination of PD-L1 positive TILs and SII could further refine prognosis in GCTs and identify three distinctive prognostic groups, which were independent of International Germ Cell Cancer Collaborative Group criteria in multivariable Cox regression analysis for OS.
Journal ArticleDOI
Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma.
Peter Kubatka,Sona Uramova,Martin Kello,Karol Kajo,Peter Kruzliak,Jan Mojzis,Desanka Vybohova,Marian Adamkov,Karina Jasek,Zora Lasabova,Pavol Zubor,Silvia Fialová,Svetlana Dokupilová,Peter Solár,Martin Péč,Katarína Adamicová,Jan Danko,Mariusz Adamek,Dietrich Büsselberg +18 more
TL;DR: This study showed a significant anticancer effect of clove buds in the mammary carcinoma model in vivo and in vitro.