J
Juan C. del Álamo
Researcher at University of California, San Diego
Publications - 133
Citations - 6169
Juan C. del Álamo is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Turbulence & Reynolds number. The author has an hindex of 33, co-authored 124 publications receiving 5183 citations. Previous affiliations of Juan C. del Álamo include Technical University of Madrid & Polytechnic University of Puerto Rico.
Papers
More filters
Journal ArticleDOI
Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment.
Shun Zhang,Danielle E. Skinner,Prateek Joshi,Ernesto Criado-Hidalgo,Yi-Ting Yeh,Juan C. Lasheras,Conor R. Caffrey,Juan C. del Álamo +7 more
TL;DR: It is shown that in unconfined settings, the parasite undergoes two-anchor marching mediated by the coordinated action of its oral and ventral suckers, which gives S. mansoni the ability to reverse its direction of locomotion without turning its body, which is likely advantageous to manoeuvre in narrow-bore vessels.
Journal ArticleDOI
Mitral Valve Prosthesis Design Affects Hemodynamic Stasis and Shear In The Dilated Left Ventricle
Vi Vu,Lorenzo Rossini,Ricardo Montes,Josue Campos,Juyeun Moon,Pablo Martinez-Legazpi,Javier Bermejo,Juan C. del Álamo,Karen May-Newman +8 more
TL;DR: The findings provide new insight about the effect of fluid dynamics on LV TE risk, and suggest that the bioprosthesis valve in the mitral position minimizes this risk by producing more physiological flow patterns in patients with diluted cardiomyopathy.
Journal ArticleDOI
An Oscillatory Contractile Pole-Force Component Dominates the Traction Forces Exerted by Migrating Amoeboid Cells
TL;DR: By compressing the mechanics of chemotaxing cells into a reduced set of temporally-resolved degrees of freedom, the present study may contribute to refined models of cell migration that incorporate cell-substrate interactions.
Journal ArticleDOI
The interplay between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3D matrices.
Joshua Francois,Joshua Francois,Adithan Kandasamy,Adithan Kandasamy,Yi-Ting Yeh,Amy B Schwartz,Cindy Ayala,Cindy Ayala,Cindy Ayala,Ruedi Meili,Shu Chien,Juan C. Lasheras,Juan C. del Álamo,Juan C. del Álamo +13 more
TL;DR: In this article, the authors investigated how chemotaxing neutrophils probe matrices and adjust their migration to collagen concentration (col) changes by tracking 20,000 cell trajectories and quantifying cell-generated 3D matrix deformations.
Journal ArticleDOI
Elucidating the Biomechanics of Leukocyte Transendothelial Migration by Quantitative Imaging.
Amy B Schwartz,Obed A Campos,Ernesto Criado-Hidalgo,Shu Chien,Juan C. del Álamo,Juan C. Lasheras,Yi-Ting Yeh +6 more
TL;DR: In this article, a review of recent advances in imaging, microfabrication, and computation now make it possible to study how cellular forces regulate VEC monolayer integrity, enable efficient pathfinding, and drive leukocyte transmigration.