Juan Yan

TL;DR: An ultrasensitive detection platform for microRNA is demonstrated by combining the tetrahedral DNA nanostructure probes and hybridization chain reaction (HCR) amplification and the uncontrolled surface immobilization and consumption of target molecules that limit the amplification efficiency of supersandwich are eliminated.

TL;DR: This protein chip thus combines the high-throughput capabilities of a microfluidic network with the high sensitivity and multicolor imaging ability offered by highly fluorescent QDs, which can become a promising diagnostic tool in clinical applications.

TL;DR: A surface-enhanced Raman scattering (SERS)-active substrate based on gold nanoparticle-decorated chemical vapor deposition (CVD)-growth graphene used for multiplexing detection of DNA and exhibits extraordinarily high sensitivity and excellent specificity for DNA detection.

TL;DR: Several single-stranded scaffold DNA, obtained from rolling circle amplification (RCA), are folded by different staples to form DNA nanoribbons, which are rigid, simple to design, and cost-effective drug carriers that show enhanced immunostimulatory activity.

TL;DR: This work designed logic gates on DNA Origami for microRNA analysis, and demonstrated that the molecular logic gates worked well with single and two input combinations.