J
Judite Costa
Researcher at University of Lisbon
Publications - 43
Citations - 951
Judite Costa is an academic researcher from University of Lisbon. The author has contributed to research in topics: Protonation & Metal ions in aqueous solution. The author has an hindex of 19, co-authored 43 publications receiving 861 citations. Previous affiliations of Judite Costa include University of Nebraska–Lincoln & Instituto Superior Técnico.
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Journal ArticleDOI
Oxidative injury in V79 Chinese hamster cells: protective role of the superoxide dismutase mimetic MnTM-4-PyP
Ana Sofia Fernandes,João Serejo,Jorge Gaspar,Fátima Cabral,Ana Bettencourt,José Rueff,Matilde Castro,Judite Costa,Nuno G. Oliveira +8 more
TL;DR: MnTM-4-PyP appears to be a promising agent for the protection against oxidative injury, however, it has shown differential responses, reinforcing the need to study different experimental models for the adequate evaluation of its potentialities as a catalytic antioxidant.
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Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide
Ana Sofia Fernandes,Jorge Gaspar,M. Fátima Cabral,José Rueff,Matilde Castro,Ines Batinic-Haberle,Judite Costa,Nuno G. Oliveira +7 more
TL;DR: Two ortho-substituted Mn(III) N-alkylpyridylporphyrins augmented markedly the total and reduced glutathione contents in TBHP-treated cells, highlighting the multiple mechanisms of protection of these SOD mimics.
Journal ArticleDOI
153Sm and 166Ho complexes with tetraaza macrocycles containing pyridine and methylcarboxylate or methylphosphonate pendant arms
Fernanda Marques,Krassimira P. Guerra,Lurdes Gano,Judite Costa,Judite Costa,M. Paula C. Campello,Luís M. P. Lima,Rita Delgado,Rita Delgado,Isabel Santos +9 more
TL;DR: A biological profile supports the in vitro instability found in serum and is consistent with the thermodynamic stability constants found for these complexes, which are hydrophilic and have a significant plasmatic protein binding.
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Remarkable inertness of copper(II) chelates of cyclen-based macrobicycles with two trans-N-acetate arms.
Catarina V. Esteves,Pedro Lamosa,Rita Delgado,Judite Costa,Pauline Désogère,Yoann Rousselin,Christine Goze,Franck Denat +7 more
TL;DR: [CuL2] exhibits the highest half-life value for a copper(II) complex of a polyazamacrocycle derivative reported in the literature until now, as revealed by the comparison of its complexation behavior with the corresponding parent compounds.
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Methyl pyridine derivatives of 14-membered tetraaza macrocycles. A new host with high selectivity for cadmium†
TL;DR: In this paper, two N-(2-pyridylmethyl) derivatives of a 14-membered tetraaza macrocycle containing pyridine have been synthesized, L1 and L2.