Krassimira P. Guerra

TL;DR: In this paper, the protonation constants of two series of tetraazamacrocyclic ligands with acetate and methylphosphonate pendant arms, as well as their stability constants with Cu 2+, La 3+, Sm 3+ and Ho 3+ were determined.

TL;DR: In this article, two N-methylphosphonic acid derivatives of a 14-membered tetraazamacrocycle containing pyridine have been synthesized, H4L1 and H6L2, and the protonation constants of these compounds and the stability constants of both ligands with Ni2+, Cu2+ and Zn2+ were determined by potentiometric methods at 298 K and ionic strength 0.10 mol dm−3 in NMe4NO3.

TL;DR: A biological profile supports the in vitro instability found in serum and is consistent with the thermodynamic stability constants found for these complexes, which are hydrophilic and have a significant plasmatic protein binding.

TL;DR: New N-(3-aminopropyl) and (2-cyanoethyl) derivatives of a 14-membered tetraazamacrocycle containing pyridine have been synthesized and revealed that the metal centres are surrounded by the four nitrogen atoms of the macrocycle and one monodentate ligand, adopting distorted square pyramidal geometries.

TL;DR: Electronic spectroscopic studies of the copper complexes revealed the involvement of catecholate groups in the coordination to the metal centre in the mono- and dinuclear copper(II) complexes, indicating that the copper( II) ion can be involved in both types of coordination site of the ligand with comparable binding affinity.