J
Judith Lorenz
Researcher at Leipzig University
Publications - 3
Citations - 9
Judith Lorenz is an academic researcher from Leipzig University. The author has contributed to research in topics: Adipogenesis & Adipose tissue. The author has co-authored 3 publications.
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Journal ArticleDOI
PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging.
Anna Kirstein,Stephanie Kehr,Michèle Nebe,Martha Hanschkow,Lisa A.G. Barth,Judith Lorenz,Melanie Penke,Jana Breitfeld,Diana Le Duc,Diana Le Duc,Kathrin Landgraf,Antje Körner,Peter Kovacs,Peter F. Stadler,Peter F. Stadler,Wieland Kiess,Antje Garten,Antje Garten +17 more
TL;DR: In this article, the role of PTEN in adipose tissue development was investigated and RNA-Seq of control and PTEN knockdown APCs was performed. And the results provided evidence that PTEN is involved in the regulation of APC proliferation, differentiation, and senescence.
Posted ContentDOI
PTEN regulates adipocyte progenitor growth, differentiation and replicative aging
Anna Kirstein,Stephanie Kehr,Michèle Nebe,Martha Hanschkow,Judith Lorenz,Melanie Penke,Jana Breitfeld,Diana Le Duc,Diana Le Duc,Kathrin Landgraf,Antje Körner,Peter Kovacs,Peter F. Stadler,Peter F. Stadler,Wieland Kiess,Antje Garten,Antje Garten +16 more
TL;DR: In this article, the role of PTEN in adipose tissue development was investigated and RNA sequencing of control and PTEN knockdown APCs was performed and it was shown that reducing PTEN levels using siRNA or CRISPR leads to an enhanced proliferation and differentiation of APCs.
Posted ContentDOI
PTEN regulates adipocyte progenitor growth, differentiation and cellular aging
Anna Kirstein,Stephanie Kehr,Michèle Nebe,Judith Lorenz,Melanie Penke,Jana Breitfeld,Diana Le Duc,Peter Kovacs,Peter F. Stadler,Wieland Kiess,Antje Garten +10 more
TL;DR: In this paper, the role of PTEN in adipose tissue development was investigated by using functional assays and RNA-sequencing of control and PTEN knockdown APCs.